Krista L Gilby
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Explore the profile of Krista L Gilby including associated specialties, affiliations and a list of published articles.
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19
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174
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Recent Articles
1.
Sharma P, Powell K, Wlodek M, OBrien T, Gilby K
Epilepsia
. 2018 Jan;
59(4):753-764.
PMID: 29377096
Objective: Aberrant myelination and developmental delay have been reported in epilepsy. However, it is unclear whether these are linked to intrinsic mechanisms that support a predisposition toward seizures and the...
2.
Sharma P, Wright D, Johnston L, Powell K, Wlodek M, Shultz S, et al.
Neurobiol Dis
. 2017 May;
104:33-40.
PMID: 28473263
Alterations in white matter integrity have been well documented in chronic epilepsy and during epileptogenesis. However, the relationship between white matter integrity and a predisposition towards epileptogenesis has been understudied....
3.
Sharma P, Dedeurwaerdere S, Vandenberg M, Fang K, Johnston L, Shultz S, et al.
Epilepsy Behav
. 2016 Nov;
65:42-48.
PMID: 27866083
Objective: The neurobiological factors underlying a predisposition towards developing epilepsy and its common behavioral comorbidities are poorly understood. FAST rats are a strain that has been selectively bred for enhanced...
4.
Rossignol E, Kobow K, Simonato M, Loeb J, Grisar T, Gilby K, et al.
Epilepsia
. 2014 Jun;
55(8):1170-86.
PMID: 24965021
New genetic investigation techniques, including next-generation sequencing, epigenetic profiling, cell lineage mapping, targeted genetic manipulation of specific neuronal cell types, stem cell reprogramming, and optogenetic manipulations within epileptic networks are...
5.
Argyropoulos A, Gilby K, Hill-Yardin E
Front Hum Neurosci
. 2013 Jul;
7:417.
PMID: 23898259
Autism spectrum disorder (ASD) patients commonly exhibit a variety of comorbid traits including seizures, anxiety, aggressive behavior, gastrointestinal problems, motor deficits, abnormal sensory processing, and sleep disturbances for which the...
6.
Gilby K, OBrien T
Epilepsy Behav
. 2013 Feb;
26(3):370-4.
PMID: 23415480
Epilepsy and autism spectrum disorder (ASD) share many primary and comorbid symptoms. The degree of clinical overlap is believed to signify a 'spectrum of vulnerability' that arises out of an...
7.
Runke D, McIntyre D, St-Onge V, Gilby K
Exp Neurol
. 2011 Feb;
229(2):259-63.
PMID: 21324316
Rat strains selectively bred to be seizure-prone (Fast) versus seizure-resistant (Slow) show differing levels of anxiety, with Slow rats displaying relatively enhanced anxiety-like behaviors to aversive stimuli. Ample data has...
8.
Azarbar A, McIntyre D, Gilby K
Behav Neurosci
. 2010 Feb;
124(1):106-114.
PMID: 20141285
Caloric restriction (CR), primarily known for extending life span, has proven anticonvulsant in several seizure models and antiepileptogenic in a strain of inherently seizure susceptible mice. Our animal model consisted...
9.
Gilby K
Can J Neurol Sci
. 2009 Sep;
36 Suppl 2:S78-81.
PMID: 19760910
Rats selectively bred to be seizure-prone versus resistant naturally exhibit behaviors, neuroanatomy and physiology that are reminiscent of attention deficit hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) in humans....
10.
McIntyre D, Gilby K
Can J Neurol Sci
. 2009 Sep;
36 Suppl 2:S33-5.
PMID: 19760897
The evidence supporting the suggestion that kindling is a good model of human temporal lobe epilepsy is briefly reviewed. Parallels between the human condition, involving both partial and secondarily generalized...