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Krishnendu Sinha

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Articles 29
Citations 901
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Recent Articles
1.
Sinha K, Ghosh N, Sil P
Toxicol Rep . 2025 Jan; 14():101877. PMID: 39844883
Machine learning (ML) has the potential to transform tobacco research and address the urgent public health crisis posed by tobacco use. Despite the well-documented health risks, cessation rates remain low....
2.
Das A, Sinha K, Chakrabarty S
Phys Chem Chem Phys . 2024 Nov; 26(46):28894-28903. PMID: 39535041
Acetylcholinesterase (AChE) has emerged as an important drug target for the treatment of neurodegenerative disorders such as Alzheimer's disease (AD). Recent experimental studies indicate that certain antidiabetic drugs can be...
3.
Sinha K, Jana S, Pramanik P, Bera B
Sci Rep . 2024 Nov; 14(1):26530. PMID: 39489740
The WRKY transcription factor gene family in soybean [Glycine max (L.) Merr.] (GmWRKY) is critical for the plant's development and stress responses. This study examines the evolutionary dynamics of the...
4.
Saha R, Chakraborty S, Sinha K, Pyne P, Pal S, Barman A, et al.
J Phys Chem Lett . 2024 Oct; 15(41):10341-10348. PMID: 39373553
Since the proposition of the Hofmeister series, guanidinium (Gdm) salts hold a special mention in protein science owing to their contrasting effect on protein(s) depending on the counteranion(s). For example,...
5.
Sen K, Kumar Das S, Ghosh N, Sinha K, Sil P
Biochem Pharmacol . 2024 Sep; 229:116545. PMID: 39293501
Lupeol, a triterpene derived from various plants, has emerged as a potent dietary supplement with extensive therapeutic potential. This review offers a comprehensive examination of lupeol's applications across diverse health...
6.
Ghosh N, Sinha K, Sil P
Chem Res Toxicol . 2024 Jul; 37(7):1071-1085. PMID: 38958636
Parkinson's disease (PD) affects more people worldwide than just aging alone can explain. This is likely due to environmental influences, genetic makeup, and changes in daily habits. The disease develops...
7.
Ghosh S, Kumar Das S, Sinha K, Ghosh B, Sen K, Ghosh N, et al.
Arch Toxicol . 2024 May; 98(8):2353-2391. PMID: 38795134
The exploration of natural products as potential agents for cancer treatment has garnered significant attention in recent years. In this comprehensive review, we delve into the diverse array of natural...
8.
Kumar Das S, Sen K, Ghosh B, Ghosh N, Sinha K, Sil P
World J Hepatol . 2024 May; 16(4):566-600. PMID: 38689743
The unique physicochemical properties inherent to nanoscale materials have unveiled numerous potential applications, spanning beyond the pharmaceutical and medical sectors into various consumer industries like food and cosmetics. Consequently, humans...
9.
Sinha K, Basu I, Shah Z, Shah S, Chakrabarty S
J Chem Inf Model . 2024 Apr; 64(9):3923-3932. PMID: 38615325
The protein PCSK9 (proprotein convertase subtilisin/Kexin type 9) negatively regulates the recycling of LDLR (low-density lipoprotein receptor), leading to an elevated plasma level of LDL. Inhibition of PCSK9-LDLR interaction has...
10.
Ghosh N, Sinha K, Sil P
Basic Clin Pharmacol Toxicol . 2024 Mar; 134(5):602-613. PMID: 38482977
Backgrounds: Neurodegenerative diseases (NDDs) such as Alzheimer's (AD) and Parkinson's (PD) are often diagnosed late, impeding effective treatment; therefore, early detection is imperative. Modern methodologies can serve a pivotal role...