Krishna Kadaveru
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Explore the profile of Krishna Kadaveru including associated specialties, affiliations and a list of published articles.
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10
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1543
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Recent Articles
1.
Campbell C, McKenney P, Konstantinovsky D, Isaeva O, Schizas M, Verter J, et al.
Nature
. 2020 May;
581(7809):475-479.
PMID: 32461639
Intestinal health relies on the immunosuppressive activity of CD4 regulatory T (T) cells. Expression of the transcription factor Foxp3 defines this lineage, and can be induced extrathymically by dietary or...
2.
Hanley M, Aladelokun O, Kadaveru K, Rosenberg D
Cancer Prev Res (Phila)
. 2019 Nov;
13(1):1-14.
PMID: 31748255
Our understanding of the role of folate one-carbon metabolism in colon carcinogenesis remains incomplete. Previous studies indicate that a methyl donor-deficient (MDD) diet lacking folic acid, choline, methionine, and vitamin...
3.
Azizi E, Carr A, Plitas G, Cornish A, Konopacki C, Prabhakaran S, et al.
Cell
. 2018 Jul;
174(5):1293-1308.e36.
PMID: 29961579
Knowledge of immune cell phenotypes in the tumor microenvironment is essential for understanding mechanisms of cancer progression and immunotherapy response. We profiled 45,000 immune cells from eight breast carcinomas, as...
4.
Boddupalli C, Bar N, Kadaveru K, Krauthammer M, Pornputtapong N, Mai Z, et al.
JCI Insight
. 2016 Dec;
1(21):e88955.
PMID: 28018970
Heterogeneity of tumor cells and their microenvironment can affect outcome in cancer. Blockade of immune checkpoints (ICPs) expressed only on a subset of immune cells leads to durable responses in...
5.
Hanley M, Kadaveru K, Perret C, Giardina C, Rosenberg D
Cancer Prev Res (Phila)
. 2016 Aug;
9(10):812-820.
PMID: 27530130
The role of folate one-carbon metabolism in colorectal cancer development is controversial, with nutritional intervention studies producing conflicting results. It has been reported that Apc mice maintained on a diet...
6.
Kadaveru K, Protiva P, Greenspan E, Kim Y, Rosenberg D
Cancer Prev Res (Phila)
. 2012 Jun;
5(7):911-20.
PMID: 22677908
Despite recent population data, the influence of dietary folate supplementation on colon cancer risk remains controversial. This study examines the effects of folate deficiency, in combination with choline, methionine, and...
7.
Vyas J, Nowling R, Meusburger T, Sargeant D, Kadaveru K, Gryk M, et al.
BMC Bioinformatics
. 2010 Jun;
11:328.
PMID: 20565705
Background: Minimotifs are short peptide sequences within one protein, which are recognized by other proteins or molecules. While there are now several minimotif databases, they are incomplete. There are reports...
8.
Montrose D, Kadaveru K, Ilsley J, Root S, Rajan T, Ramesh M, et al.
Toxicol Sci
. 2010 Jun;
117(1):122-32.
PMID: 20562220
Cytosolic phospholipase A(2) (cPLA(2)) is the rate-limiting enzyme responsible for the generation of prostaglandins (PGs), which are bioactive lipids that play critical roles in maintaining gastrointestinal (GI) homeostasis. There has...
9.
Rajasekaran S, Balla S, Gradie P, Gryk M, Kadaveru K, Kundeti V, et al.
Nucleic Acids Res
. 2008 Nov;
37(Database issue):D185-90.
PMID: 18978024
Minimotif Miner (MnM) consists of a minimotif database and a web-based application that enables prediction of motif-based functions in user-supplied protein queries. We have revised MnM by expanding the database...
10.
Kadaveru K, Vyas J, Schiller M
Front Biosci
. 2008 May;
13:6455-71.
PMID: 18508672
Short functional peptide motifs cooperate in many molecular functions including protein interactions, protein trafficking, and posttranslational modifications. Viruses exploit these motifs as a principal mechanism for hijacking cells and many...