Kranthi Varala
Overview
Explore the profile of Kranthi Varala including associated specialties, affiliations and a list of published articles.
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29
Citations
1271
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Recent Articles
1.
Ranjan R, Srijan S, Balekuttira S, Agarwal T, Ramey M, Dobbins M, et al.
Proc Natl Acad Sci U S A
. 2024 Apr;
121(18):e2322751121.
PMID: 38652750
Organ-specific gene expression datasets that include hundreds to thousands of experiments allow the reconstruction of organ-level gene regulatory networks (GRNs). However, creating such datasets is greatly hampered by the requirements...
2.
Stevenson D, Ramakrishnan S, de Santis Alves C, Coelho L, Kramer M, Goodwin S, et al.
bioRxiv
. 2023 Sep;
PMID: 37662366
We present the genome of the living fossil, , a southern hemisphere conifer morphologically unchanged since the Cretaceous. Presumed extinct until rediscovery in 1994, the Wollemi pine is critically endangered...
3.
Agarwal T, Wang X, Mildenhall F, Ibrahim I, Puthiyaveetil S, Varala K
Hortic Res
. 2023 Aug;
10(8):uhad137.
PMID: 37564269
Improving chilling tolerance in cold-sensitive crops, e.g. tomato, requires knowledge of the early molecular response to low temperature in these under-studied species. To elucidate early responding processes and regulators, we...
4.
Li L, Garsamo M, Yuan J, Wang X, Lam S, Varala K, et al.
Front Plant Sci
. 2022 Aug;
13:866086.
PMID: 35968124
The dynamic assembly of SKP1•CUL1•F-box protein (SCF) ubiquitin ligases is important for protein ubiquitination and degradation. This process is enabled by CAND1, which exchanges F-box proteins associated with the common...
5.
Dussarrat T, Prigent S, Latorre C, Bernillon S, Flandin A, Diaz F, et al.
New Phytol
. 2022 Mar;
234(5):1614-1628.
PMID: 35288949
Current crop yield of the best ideotypes is stagnating and threatened by climate change. In this scenario, understanding wild plant adaptations in extreme ecosystems offers an opportunity to learn about...
6.
Eshel G, Araus V, Undurraga S, Soto D, Moraga C, Montecinos A, et al.
Proc Natl Acad Sci U S A
. 2021 Nov;
118(46).
PMID: 34725254
The Atacama Desert in Chile-hyperarid and with high-ultraviolet irradiance levels-is one of the harshest environments on Earth. Yet, dozens of species grow there, including Atacama-endemic plants. Herein, we establish the...
7.
Cheng C, Li Y, Varala K, Bubert J, Huang J, Kim G, et al.
Nat Commun
. 2021 Sep;
12(1):5627.
PMID: 34561450
Inferring phenotypic outcomes from genomic features is both a promise and challenge for systems biology. Using gene expression data to predict phenotypic outcomes, and functionally validating the genes with predictive...
8.
McCoy R, Julian R, Kumar S, Ranjan R, Varala K, Li Y
Plants (Basel)
. 2021 Mar;
10(2).
PMID: 33668664
Upon sensing developmental or environmental cues, epigenetic regulators transform the chromatin landscape of a network of genes to modulate their expression and dictate adequate cellular and organismal responses. Knowledge of...
9.
Alvarez J, Schinke A, Brooks M, Pasquino A, Leonelli L, Varala K, et al.
Nat Commun
. 2020 Mar;
11(1):1157.
PMID: 32123177
Dynamic reprogramming of gene regulatory networks (GRNs) enables organisms to rapidly respond to environmental perturbation. However, the underlying transient interactions between transcription factors (TFs) and genome-wide targets typically elude biochemical...
10.
Brooks M, Cirrone J, Pasquino A, Alvarez J, Swift J, Mittal S, et al.
Nat Commun
. 2019 Apr;
10(1):1569.
PMID: 30952851
Charting a temporal path in gene networks requires linking early transcription factor (TF)-triggered events to downstream effects. We scale-up a cell-based TF-perturbation assay to identify direct regulated targets of 33...