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Kourtney P Nickerson

Explore the profile of Kourtney P Nickerson including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 688
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Recent Articles
1.
Nickerson K, Llanos-Chea A, Ingano L, Serena G, Miranda-Ribera A, Perlman M, et al.
Microbiol Spectr . 2021 Jun; 9(1):e0000321. PMID: 34106568
Gastrointestinal infections cause significant morbidity and mortality worldwide. The complexity of human biology and limited insights into host-specific infection mechanisms are key barriers to current therapeutic development. Here, we demonstrate...
2.
Charles R, Kelly M, Tam J, Akter A, Hossain M, Islam K, et al.
mBio . 2020 Nov; 11(6). PMID: 33203761
The mechanism of protection against cholera afforded by previous illness or vaccination is currently unknown. We have recently shown that antibodies targeting O-specific polysaccharide (OSP) of correlate highly with protection...
3.
Gipson K, Nickerson K, Drenkard E, Llanos-Chea A, Dogiparthi S, Lanter B, et al.
Infect Immun . 2020 Jul; 88(10). PMID: 32661122
Throughout the course of infection, many pathogens encounter bactericidal conditions that threaten the viability of the bacteria and impede the establishment of infection. Bile is one of the most innately...
4.
Verma S, Prescott R, Ingano L, Nickerson K, Hill E, Faherty C, et al.
Gut Microbes . 2019 Dec; 11(3):526-538. PMID: 31829769
serovar Typhi is the etiologic agent of typhoid fever, a major public health problem in the developing world. Moving toward and adhering to the intestinal epithelium represents key initial steps...
5.
Chanin R, Nickerson K, Llanos-Chea A, Sistrunk J, Rasko D, Kumar D, et al.
mSphere . 2019 Nov; 4(6). PMID: 31722995
The species are Gram-negative, facultative intracellular pathogens that invade the colonic epithelium and cause significant diarrheal disease. Despite extensive research on the pathogen, a comprehensive understanding of how initiates contact...
6.
Leonard M, Bai Y, Serena G, Nickerson K, Camhi S, Sturgeon C, et al.
PLoS One . 2019 Apr; 14(4):e0215132. PMID: 30998704
Background & Aims: The early steps in the pathophysiology of celiac disease (CD) leading to loss of tolerance to gluten are poorly described. Our aim was to use RNA sequencing...
7.
Llanos-Chea A, Citorik R, Nickerson K, Ingano L, Serena G, Senger S, et al.
J Pediatr Gastroenterol Nutr . 2018 Nov; 68(4):509-516. PMID: 30418409
Objective: Enteric bacterial pathogens cause diarrheal disease and mortality at significant rates throughout the world, particularly in children younger than 5 years. Our ability to combat bacterial pathogens has been...
8.
Nickerson K, Faherty C
J Vis Exp . 2018 May; (135). PMID: 29781989
Biofilm formation is a dynamic, multistage process that occurs in bacteria under harsh environmental conditions or times of stress. For enteric pathogens, a significant stress response is induced during gastrointestinal...
9.
Rodriguez-Palacios A, Harding A, Menghini P, Himmelman C, Retuerto M, Nickerson K, et al.
Inflamm Bowel Dis . 2018 Mar; 24(5):1005-1020. PMID: 29554272
Background: Epidemiological studies indicate that the use of artificial sweeteners doubles the risk for Crohn's disease (CD). Herein, we experimentally quantified the impact of 6-week supplementation with a commercial sweetener...
10.
Kessler S, Obery D, Nickerson K, Petrey A, McDonald C, de la Motte C
J Histochem Cytochem . 2018 Jan; 66(4):273-287. PMID: 29290146
Intestinal epithelium plays a critical role in host defense against orally acquired pathogens. Dysregulation of this protective barrier is a primary driver of inflammatory bowel diseases (Crohn's and ulcerative colitis)...