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Kostas Bethanis

Explore the profile of Kostas Bethanis including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 94
Followers 0
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Recent Articles
1.
Kamatsos F, Drosou M, Zarkadoulas A, Bethanis K, Mitsopoulou C, Mitsopoulou C
Chemistry . 2025 Jan; :e202404396. PMID: 39868769
The prominence of binuclear, bimetallic catalysts underlines the need for the design and development of diverse bifunctional ligand frameworks that exhibit tunable electronic and structural properties. Such strategies enable metal-metal...
2.
Araj S, Szeleszczuk L, Gubica T, Zielinska-Pisklak M, Bethanis K, Christoforides E, et al.
J Pharm Biomed Anal . 2024 Sep; 252:116474. PMID: 39298839
N-Phenylacetyl-L-prolylglycine ethyl ester (Noopept, GVS-111, omberacetam) is an orally available active pharmaceutical ingredient (API), with neuroprotective properties and ability to enhance cognitive function. It belongs to nootropic family of drugs...
3.
Mazurek A, Szeleszczuk L, Bethanis K, Christoforides E, Dudek M, Zielinska-Pisklak M, et al.
Molecules . 2023 May; 28(9). PMID: 37175157
17-β-estradiol (EST) is the most potent form of naturally occurring estrogens; therefore, it has found a wide pharmaceutical application. The major problem associated with the use of EST is its...
4.
Christoforides E, Andreou A, Papaioannou A, Bethanis K
Biomolecules . 2022 Dec; 12(12). PMID: 36551190
Piperine (PN), the primary pungent alkaloid in black pepper shows several biological activities such as antioxidant, antimicrobial and anti-cancerogenic effects. Similar to other alkaloids, PN is characterized by poor water...
5.
Tziveleka L, Kikionis S, Karkatzoulis L, Bethanis K, Roussis V, Ioannou E
Mar Drugs . 2022 Nov; 20(11). PMID: 36354987
In search of alternative and sustainable sources of collagenous materials for biomedical applications, the scales of five Mediterranean fish species-fished in high tonnage in the Mediterranean region since they represent...
6.
Hatziagapiou K, Bethanis K, Koniari E, Christoforides E, Nikola O, Andreou A, et al.
Pharmaceutics . 2022 Apr; 14(4). PMID: 35456540
Phytocannabinoids possess anticancer properties, as established in vitro and in vivo. However, they are characterized by high lipophilicity. To improve the properties of cannabidiol (CBD), such as solubility, stability, and...
7.
Chiniadis L, Bratsos I, Bethanis K, Karpusas M, Giastas P, Papakyriakou A
J Biol Inorg Chem . 2020 Apr; 25(4):635-645. PMID: 32266561
The high-resolution X-ray crystal structures of the adducts formed between the "half sandwich"-type Ru(II) coordination compound [Ru(1,4,7-trithiacyclononane)(ethane-1,2-diamine)Cl] and two proteins, namely hen egg-white lysozyme and proteinase K, are presented. The...
8.
Andreou A, Giastas P, Arnaouteli S, Tzanodaskalaki M, Tzartos S, Bethanis K, et al.
Acta Crystallogr F Struct Biol Commun . 2019 Apr; 75(Pt 4):312-320. PMID: 30950833
Ba0331 is a putative polysaccharide deacetylase from Bacillus anthracis, the etiological agent of the disease anthrax, that contributes to adaptation of the bacterium under extreme conditions and to maintenance of...
9.
Christoforides E, Papaioannou A, Bethanis K
Beilstein J Org Chem . 2018 May; 14:838-848. PMID: 29719578
The role of beta-cyclodextrin (β-CD) in cholesterol removal primarily from mammalian cells and secondly from dairy products has been studied thoroughly in recent years. Although the physicochemical characterization of the...
10.
Kakouri E, Hatziagapiou K, Bethanis K, Nikola O, Lambrou G, Tarantilis P
Crit Rev Oncog . 2018 Apr; 22(3-4):263-273. PMID: 29604903
Cancer is a growing problem because it is a chronic disease that affects, not only patient health, but also its daily living. Concurrent cancer therapies have ameliorated cancer prevalence, but...