Kosha Ruparel
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Explore the profile of Kosha Ruparel including associated specialties, affiliations and a list of published articles.
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149
Citations
9232
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Recent Articles
1.
Pecsok M, Robinson H, Atkins A, Calkins M, Elliott M, Mordy A, et al.
Front Aging Neurosci
. 2025 Feb;
16:1535158.
PMID: 39926356
Introduction: Hippocampal glutamate (Glu) dysfunction is a pertinent indicator of neurodegeneration, yet mapping typical age-related changes in Glu has been challenging. Here, we use a 7T MRI approach, Glutamate Chemical...
2.
Calkins M, Ered A, Moore T, White L, Taylor J, Moxam A, et al.
Schizophr Bull
. 2025 Jan;
PMID: 39792431
Background And Hypothesis: Improvements in screening tools for early subthreshold psychosis symptoms are needed to facilitate early identification and intervention efforts, especially given the challenges of rapidly differentiating age-appropriate experiences...
3.
Souders M, McDonald-McGinn D, Ruparel K, Moore T, Tang S, Calkins M, et al.
Psychiatry Res
. 2024 Dec;
344():116336.
PMID: 39731884
The 22q11.2 Deletion Syndrome (22q11.2DS) is a multisystem genetic disorder with prominent sleep disturbances, neuropsychiatric conditions and neurocognitive challenges. Poor sleep can impact cognitive development, psychopathology and daily functioning. An...
4.
Cooper E, Schindler M, Bar-Or A, Brandstadter R, Calkins M, Gur R, et al.
medRxiv
. 2024 Oct;
PMID: 39464257
Multiple sclerosis (MS) is an immune-mediated neurological disorder that affects one million people in the United States. Up to 50% of people with MS experience depression, yet the mechanisms of...
5.
Gur R, Bearden C, Jacquemont S, Swillen A, van Amelsvoort T, van den Bree M, et al.
Mol Psychiatry
. 2024 Jul;
30(2):379-387.
PMID: 39048645
Rare recurrent copy number variants (CNVs) at chromosomal loci 22q11.2 and 16p11.2 are genetic disorders with lifespan risk for neuropsychiatric disorders. Microdeletions and duplications are associated with neurocognitive deficits, yet...
6.
Roalf D, McDonald-McGinn D, Jee J, Krall M, Crowley T, Moberg P, et al.
J Neurodev Disord
. 2024 Jun;
16(1):35.
PMID: 38918700
Background: Minor physical anomalies (MPAs) are congenital morphological abnormalities linked to disruptions of fetal development. MPAs are common in 22q11.2 deletion syndrome (22q11DS) and psychosis spectrum disorders (PS) and likely...
7.
Zoupou E, Moore T, Kennedy K, Calkins M, Gorgone A, Di Sandro A, et al.
Psychiatry Res
. 2024 Mar;
335:115862.
PMID: 38554493
Large-scale studies and burdened clinical settings require precise, efficient measures that assess multiple domains of psychopathology. Computerized adaptive tests (CATs) can reduce administration time without compromising data quality. We examined...
8.
Wannan C, Nelson B, Addington J, Allott K, Anticevic A, Arango C, et al.
Schizophr Bull
. 2024 Mar;
50(3):496-512.
PMID: 38451304
This article describes the rationale, aims, and methodology of the Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ). This is the largest international collaboration to date that will develop algorithms to predict...
9.
Gur R, Bearden C, Jacquemont S, Jizi K, Amelsvoort van T, van den Bree M, et al.
Res Sq
. 2024 Jan;
PMID: 38234766
Rare recurrent copy number variants (CNVs) at chromosomal loci 22q11.2 and 16p11.2 are among the most common rare genetic disorders associated with significant risk for neuropsychiatric disorders across the lifespan....
10.
Source-based morphometry reveals structural brain pattern abnormalities in 22q11.2 deletion syndrome
Ge R, Ching C, Bassett A, Kushan L, Antshel K, van Amelsvoort T, et al.
Hum Brain Mapp
. 2024 Jan;
45(1):e26553.
PMID: 38224541
22q11.2 deletion syndrome (22q11DS) is the most frequently occurring microdeletion in humans. It is associated with a significant impact on brain structure, including prominent reductions in gray matter volume (GMV),...