Konstantinos Aliazis
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Explore the profile of Konstantinos Aliazis including associated specialties, affiliations and a list of published articles.
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10
Citations
101
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Recent Articles
1.
Aliazis K, Yenyuwadee S, Phikulsod P, Boussiotis V
Br J Haematol
. 2024 Jul;
205(3):798-811.
PMID: 39044285
Cells of the innate and adaptive immune systems are the progeny of haematopoietic stem and progenitor cells (HSPCs). During steady-state myelopoiesis, HSPC undergo differentiation and proliferation but are called to...
2.
Aliazis K, Boussiotis V
Cell Rep Med
. 2024 Jan;
5(1):101378.
PMID: 38232704
A study by Régnier et al. shows that Flt3-ligand (FL) levels program two distinct mechanisms of anti-tumor immunity. Low FL levels allow recruitment of T effectors and T cell-mediated responses...
3.
Ibis B, Aliazis K, Cao C, Yenyuwadee S, Boussiotis V
Front Immunol
. 2023 Jun;
14:1197364.
PMID: 37342323
During the past decade, there has been a revolution in cancer therapeutics by the emergence of antibody-based immunotherapies that modulate immune responses against tumors. These therapies have offered treatment options...
4.
Yeo A, Shah R, Aliazis K, Pal R, Xu T, Zhang P, et al.
Cancer Immunol Res
. 2023 Mar;
11(5):629-645.
PMID: 36881002
The composition of the tumor immune microenvironment (TIME) is considered a key determinant of patients' response to immunotherapy. The mechanisms underlying TIME formation and development over time are poorly understood....
5.
Christofides A, Katopodi X, Cao C, Karagkouni D, Aliazis K, Yenyuwadee S, et al.
Nat Immunol
. 2022 Dec;
24(1):55-68.
PMID: 36581713
The inhibitory receptor PD-1 suppresses T cell activation by recruiting the phosphatase SHP-2. However, mice with a T-cell-specific deletion of SHP-2 do not have improved antitumor immunity. Here we showed...
6.
Yenyuwadee S, Aliazis K, Wang Q, Christofides A, Shah R, Patsoukis N, et al.
Semin Cancer Biol
. 2022 Aug;
86(Pt 2):187-201.
PMID: 35985559
During the past decade there has been a revolution in cancer therapeutics by the emergence of antibody-based and cell-based immunotherapies that modulate immune responses against tumors. These new therapies have...
7.
Anastasilakis A, Papachatzopoulos S, Makras P, Gkiomisi A, Nikolakopoulos P, Polyzos S, et al.
Bone
. 2022 Feb;
158:116354.
PMID: 35150909
Introduction: GnRH-analogs induce bone loss. We aimed to investigate the effects of goserelin-induced menstrual cessation (MC) and subsequent menstrual restoration (MR) on bone metabolism (BM). Methods: In this prospective cohort...
8.
Wiggins B, Pallett L, Li X, Davies S, Amin O, Gill U, et al.
Gut
. 2021 Sep;
71(7):1399-1411.
PMID: 34548339
Objective: Tissue-resident memory T cells (T) are vital immune sentinels that provide protective immunity. While hepatic CD8 T have been well described, little is known about the location, phenotype and...
9.
Abdullah N, Ahemad N, Aliazis K, Khairat J, Lee T, Abdul Ahmad S, et al.
Viruses
. 2021 Jun;
13(6).
PMID: 34071712
Alphavirus non-structural proteins 1-4 (nsP1, nsP2, nsP3, and nsP4) are known to be crucial for alphavirus RNA replication and translation. To date, nsP3 has been demonstrated to mediate many virus-host...
10.
Wiggins B, Aliazis K, Davies S, Hirschfield G, Lalor P, Reynolds G, et al.
Methods Mol Biol
. 2017 Mar;
1591:195-214.
PMID: 28349484
The liver is the largest internal organ and filters around 3 pints of blood per minute. This continuous flux of blood should not be confused with rapid egress of lymphocytes...