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Konstantina Chanoumidou

Explore the profile of Konstantina Chanoumidou including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 219
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Recent Articles
1.
Zota I, Chanoumidou K, Gravanis A, Charalampopoulos I
Front Cell Neurosci . 2024 Sep; 18:1422130. PMID: 39285941
Alzheimer's Disease (AD) is a chronic neurodegenerative disorder constituting the most common form of dementia (60%-70% of cases). Although AD presents majorly a neurodegenerative pathology, recent clinical evidence highlights myelin...
2.
Zota I, Chanoumidou K, Charalampopoulos I, Gravanis A
Glia . 2024 Jan; 72(4):809-827. PMID: 38205694
Recent findings highlight myelin breakdown as a decisive early event in Alzheimer's Disease (AD) acting as aggravating factor of its progression. However, it is still unclear whether myelin loss is...
3.
Papadopoulou M, Rogdakis T, Charou D, Peteinareli M, Ntarntani K, Gravanis A, et al.
Int J Mol Sci . 2023 Jul; 24(14). PMID: 37511441
Neuronal cell fate is predominantly controlled based on the effects of growth factors, such as neurotrophins, and the activation of a variety of signaling pathways acting through neurotrophin receptors, namely...
4.
Chanoumidou K, Hernandez-Rodriguez B, Windener F, Thomas C, Stehling M, Mozafari S, et al.
Stem Cell Reports . 2021 Mar; 16(4):771-783. PMID: 33770499
Limited access to human oligodendrocytes impairs better understanding of oligodendrocyte pathology in myelin diseases. Here, we describe a method to robustly convert human fibroblasts directly into oligodendrocyte-like cells (dc-hiOLs), which...
5.
Chanoumidou K, Mozafari S, Baron-Van Evercooren A, Kuhlmann T
Glia . 2019 Oct; 68(4):705-720. PMID: 31633852
Oligodendroglial pathology is central to de- and dysmyelinating, but also contributes to neurodegenerative and psychiatric diseases as well as brain injury. The understanding of oligodendroglial biology in health and disease...
6.
Chanoumidou K, Hadjimichael C, Athanasouli P, Ahlenius H, Klonizakis A, Nikolaou C, et al.
Sci Rep . 2018 Sep; 8(1):13790. PMID: 30214018
Groucho related gene 5 (GRG5) is a multifunctional protein that has been implicated in late embryonic and postnatal mouse development. Here, we describe a previously unknown role of GRG5 in...
7.
Hadjimichael C, Chanoumidou K, Nikolaou C, Klonizakis A, Theodosi G, Makatounakis T, et al.
Stem Cell Reports . 2017 Apr; 8(5):1366-1378. PMID: 28392218
Promyelocytic leukemia protein (PML), the main constituent of PML nuclear bodies, regulates various physiological processes in different cell types. However, little is known about its functions in embryonic stem cells...
8.
Hadjimichael C, Chanoumidou K, Papadopoulou N, Arampatzi P, Papamatheakis J, Kretsovali A
World J Stem Cells . 2015 Oct; 7(9):1150-84. PMID: 26516408
Pluripotency of embryonic stem cells (ESCs) and induced pluripotent stem cells is regulated by a well characterized gene transcription circuitry. The circuitry is assembled by ESC specific transcription factors, signal...
9.
Klanert G, Jadhav V, Chanoumidou K, Grillari J, Borth N, Hackl M
Biotechnol J . 2013 Dec; 9(4):538-44. PMID: 24323929
MicroRNAs (miRNAs) are small non-coding RNAs (∼22 nucleotides) which regulate gene expression by silencing mRNA translation. MiRNAs are transcribed as long primary transcripts, which are enzymatically processed by Drosha/Dgcr8, in...