Konstantin N Yarygin
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Explore the profile of Konstantin N Yarygin including associated specialties, affiliations and a list of published articles.
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24
Citations
244
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Recent Articles
1.
Kim Y, Lupatov A, Burunova V, Bagmet N, Chardarov N, Malov S, et al.
Int J Mol Sci
. 2025 Jan;
25(24.
PMID: 39769138
Every 25th death worldwide is associated with liver pathology. The development of novel approaches to liver diseases therapy and protocols for maintaining the vital functions of patients on the liver...
2.
Vakhrushev I, Basok Y, Baskaev K, Novikova V, Leonov G, Grigoriev A, et al.
Int J Mol Sci
. 2024 Jun;
25(11).
PMID: 38891883
Articular cartilage damage still remains a major problem in orthopedical surgery. The development of tissue engineering techniques such as autologous chondrocyte implantation is a promising way to improve clinical outcomes....
3.
Kholodenko I, Yarygin K
Biomedicines
. 2023 Nov;
11(11).
PMID: 38002056
Non-alcoholic steatohepatitis (NASH) is a serious public health issue associated with the obesity pandemic. Obesity is the main risk factor for the non-alcoholic fatty liver disease (NAFLD), which progresses to...
4.
The Crosstalk between Mesenchymal Stromal/Stem Cells and Hepatocytes in Homeostasis and under Stress
Kholodenko I, Kholodenko R, Yarygin K
Int J Mol Sci
. 2023 Oct;
24(20).
PMID: 37894893
Liver diseases, characterized by high morbidity and mortality, represent a substantial medical problem globally. The current therapeutic approaches are mainly aimed at reducing symptoms and slowing down the progression of...
5.
Cherkashova E, Namestnikova D, Gubskiy I, Revkova V, Sukhinich K, Melnikov P, et al.
Life (Basel)
. 2023 Feb;
13(2).
PMID: 36836645
Systemic transplantation of mesenchymal stem cells (MSCs) is a promising approach for the treatment of ischemia-associated disorders, including stroke. However, exact mechanisms underlying its beneficial effects are still debated. In...
6.
Kholodenko I, Kholodenko R, Majouga A, Yarygin K
Curr Issues Mol Biol
. 2022 Nov;
44(11):5153-5172.
PMID: 36354663
Over the past two decades, mesenchymal stem cells (MSCs) have shown promising therapeutic effects both in preclinical studies (in animal models of a wide range of diseases) and in clinical...
7.
Lupatov A, Yarygin K
Biomedicines
. 2022 Oct;
10(10).
PMID: 36289597
Stem cells serve as a source of cellular material in embryogenesis and postnatal growth and regeneration. This requires significant proliferative potential ensured by sufficient telomere length. Telomere attrition in the...
8.
Kim Y, Potashnikova D, Gisina A, Kholodenko I, Kopylov A, Tikhonova O, et al.
Int J Mol Sci
. 2022 Sep;
23(17).
PMID: 36077272
CD133 is an extensively studied marker of the most malignant tumor cell population, designated as cancer stem cells (CSCs). However, the function of this glycoprotein and its involvement in cell...
9.
Kholodenko I, Gisina A, Manukyan G, Majouga A, Svirshchevskaya E, Kholodenko R, et al.
Curr Issues Mol Biol
. 2022 Aug;
44(8):3428-3443.
PMID: 36005132
Mesenchymal stem cells (MSCs) have a pronounced therapeutic potential in various pathological conditions. Though therapeutic effects of MSC transplantation have been studied for a long time, the underlying mechanisms are...
10.
Gubskiy I, Namestnikova D, Revkova V, Cherkashova E, Sukhinich K, Beregov M, et al.
Biomedicines
. 2022 Feb;
10(2).
PMID: 35203560
Intra-arterial (IA) mesenchymal stem cells (MSCs) transplantation providing targeted cell delivery to brain tissue is a promising approach to the treatment of neurological disorders, including stroke. Factors determining cell distribution...