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Konstantin G Kousoulas

Explore the profile of Konstantin G Kousoulas including associated specialties, affiliations and a list of published articles. Areas
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Articles 90
Citations 1739
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Recent Articles
11.
Roy T, Banang-Mbeumi S, Boateng S, Ruiz E, Chamcheu R, Kang L, et al.
Front Immunol . 2023 Feb; 13:1075804. PMID: 36741386
Psoriasis is a chronic autoimmune inflammatory skin disorder characterized by epidermal hyperplasia and aberrant immune response. In addition to aberrant cytokine production, psoriasis is associated with activation of the Akt/mTOR...
12.
Singha M, Pu L, Stanfield B, Uche I, Rider P, Kousoulas K, et al.
BMC Cancer . 2022 Nov; 22(1):1211. PMID: 36434556
Background: Vast amounts of rapidly accumulating biological data related to cancer and a remarkable progress in the field of artificial intelligence (AI) have paved the way for precision oncology. Our...
13.
Collantes T, Clark C, Musarrat F, Jambunathan N, Jois S, Kousoulas K
Viruses . 2022 Oct; 14(10). PMID: 36298744
The alphaherpesvirus UL37 tegument protein is a highly conserved, multi-functional protein. Mutagenesis analysis delineated the UL37 domains necessary for retrograde transport and viral replication. Specifically, the amino-terminal 480 amino acids...
14.
Stanfield B, Bravo F, Dixon D, Chouljenko V, Kousoulas K, Bernstein D
Vaccine . 2022 Sep; 40(42):6093-6099. PMID: 36114130
Herpes simplex virus type 1 and 2 (HSV-1 and HSV-2 respectively) cause life-long latent infections resulting in recurrent orofacial and genital blisters or sores. Ensued disease can be painful and...
15.
Kubra K, Akhter M, Saini Y, Kousoulas K, Barabutis N
Cell Signal . 2022 Aug; 99:110432. PMID: 35933031
Background: Endothelial hyperpermeability is associated with sepsis and acute respiratory distress syndrome (ARDS). The identification of molecular pathways involved in barrier dysfunction; may reveal promising therapeutic targets to combat ARDS....
16.
Rider P, Kamil M, Yilmaz I, Atmaca H, Kalkan-Yazici M, Doymaz M, et al.
Vaccines (Basel) . 2022 Feb; 10(2). PMID: 35214758
Here, we present the construction of an attenuated herpes simplex virus type-1 (HSV-1)-vectored vaccine, expressing three liver-stage (LS) malaria parasite exported proteins (EXP1, UIS3 and TMP21) as fusion proteins with...
17.
Uche I, Stanfield B, Rudd J, Kousoulas K, Rider P
Front Mol Biosci . 2022 Feb; 9:832393. PMID: 35155582
Current approaches to cancer immunotherapy include immune checkpoint inhibitors, cancer vaccines, and adoptive cellular therapy. These therapies have produced significant clinical success for specific cancers, but their efficacy has been...
18.
Dahal A, Sonju J, Kousoulas K, Jois S
Pept Sci (Hoboken) . 2021 Dec; 114(1):e24245. PMID: 34901700
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Covid-19 pandemic has caused high morbidity and mortality rates worldwide. Virus entry into cells can be blocked using several strategies, including inhibition of...
19.
Nabi R, Lewin A, Collantes T, Chouljenko V, Kousoulas K
Front Immunol . 2021 Dec; 12:789454. PMID: 34868077
Herpes simplex virus type-1 (HSV-1) ocular infection is one of the leading causes of infectious blindness in developed countries. The resultant herpetic keratitis (HK) is caused by an exacerbated reaction...
20.
Jambunathan N, Clark C, Musarrat F, Chouljenko V, Rudd J, Kousoulas K
Viruses . 2021 Sep; 13(9). PMID: 34578430
Herpes simplex virus type-1 (HSV-1) and type-2 (HSV-2) are prototypical alphaherpesviruses that are characterized by their unique properties to infect trigeminal and dorsal root ganglionic neurons, respectively, and establish life-long...