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» Authors » Konstantin G Arbeev

Konstantin G Arbeev

Explore the profile of Konstantin G Arbeev including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 109
Citations 1758
Followers 0
Related Specialties
Geriatrics
Public Health
Physiology
Top 10 Co-Authors
Svetlana V Ukraintseva
Anatoliy I Yashin
Alexander M Kulminski
Anatoli I Yashin
Igor Akushevich
Deqing Wu
Eric Stallard
Irina Culminskaya
Olivia Bagley
Kaare Christensen
Published In
Front Genet
Mech Ageing Dev
J Gerontol A Biol Sci Med Sci
Rejuvenation Res
Exp Gerontol
Affiliations
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Recent Articles
1.
APOE4 and infectious diseases jointly contribute to brain glucose hypometabolism, a biomarker of Alzheimer's pathology: New findings from the ADNI
Lathika Rajendrakumar A, Arbeev K, Bagley O, Duan M, Yashin A, Ukraintseva S
PLoS One . 2025 Jan; 20(1):e0316808. PMID: 39774485
Background: Impaired brain glucose metabolism is a preclinical feature of neurodegenerative diseases such as Alzheimer's disease (AD). Infections may promote AD-related pathology. Therefore, we investigated the interplay between infections and...
2.
SNP rs6543176 is associated with extreme human longevity but increased risk for cancer
Gurinovich A, Song Z, Bae H, Leshchyk A, Li M, Lords H, et al.
Geroscience . 2025 Jan; PMID: 39751714
Using whole-genome sequencing (WGS) might offer insights into rare genetic variants associated with healthy aging and extreme longevity (EL), potentially pointing to useful therapeutic targets. In this study, we conducted...
3.
Elevated blood glucose levels are associated with the progression of brain hypometabolism, and HDL-C and add to this association
Lathika Rajendrakumar A, Ukraintseva S, Bagley O, Duan M, Yashin A, Arbeev K
medRxiv . 2024 Oct; PMID: 39399037
Background: Brain glucose hypometabolism has consistently been found in neurodegenerative disorders, including Alzheimer's disease (AD). High blood glucose and HDL cholesterol (HDL-C) levels have also been linked to neurodegeneration and...
4.
and Infectious Diseases Jointly Contribute to Brain Glucose Hypometabolism, a Biomarker of Alzheimer's Pathology: New Findings from the ADNI
Lathika Rajendrakumar A, Arbeev K, Bagley O, Duan M, Yashin A, Ukraintseva S
medRxiv . 2024 Sep; PMID: 39314962
Background: Impaired brain glucose metabolism is a preclinical feature of neurodegenerative diseases such as Alzheimer's disease (AD). Infections may promote AD-related pathology. Therefore, we investigated the interplay between infections and...
5.
The association between rs6859 in gene and Alzheimer's disease is partly mediated by pTau
Lathika Rajendrakumar A, Arbeev K, Bagley O, Yashin A, Ukraintseva S
Front Aging Neurosci . 2024 Aug; 16:1388363. PMID: 39165837
Introduction: Emerging evidence suggests a connection between vulnerability to infections and Alzheimer's disease (AD). The nectin cell adhesion molecule 2 gene coding for a membrane component of adherens junctions is...
6.
Traffic-related air pollution and can synergistically affect hippocampal volume in older women: new findings from UK Biobank
Popov V, Ukraintseva S, Duan H, Yashin A, Arbeev K
Front Dement . 2024 Aug; 3:1402091. PMID: 39135618
A growing research body supports the connection between neurodegenerative disorders, including Alzheimer's disease (AD), and traffic-related air pollution (TRAP). However, the underlying mechanisms are not well understood. A deeper investigation...
7.
Methods for joint modelling of longitudinal omics data and time-to-event outcomes: Applications to lysophosphatidylcholines in connection to aging and mortality in the Long Life Family Study
Arbeev K, Bagley O, Ukraintseva S, Kulminski A, Stallard E, Schwaiger-Haber M, et al.
medRxiv . 2024 Aug; PMID: 39132492
Studying relationships between longitudinal changes in omics variables and risks of events requires specific methodologies for joint analyses of longitudinal and time-to-event outcomes. We applied two such approaches (joint models...
8.
The association between rs6859 in gene and Alzheimer's disease is partly mediated by pTau
Lathika Rajendrakumar A, Arbeev K, Bagley O, Yashin A, Ukraintseva S
medRxiv . 2024 Jul; PMID: 38947013
Introduction: Emerging evidence suggests a connection between vulnerability to infections and Alzheimer's disease (AD). The nectin cell adhesion molecule 2 gene coding for a membrane component of adherens junctions is...
9.
End of Life Events and Causes of Death in Danish Long-Lived Siblings: Reduced Dementia Risk Compared to Sporadic Long-Livers
Galvin A, Pedersen J, Arbeev K, Feitosa M, Ukraintseva S, Yao S, et al.
J Alzheimers Dis . 2024 May; 99(4):1397-1407. PMID: 38788069
Background: Better physical robustness and resilience of long-lived siblings compared to sporadic long-livers has been demonstrated in several studies. However, it is unknown whether long-lived siblings also end their lives...
10.
Prior infections are associated with smaller hippocampal volume in older women
Popov V, Ukraintseva S, Duan H, Arbeev K, Yashin A
Front Dement . 2024 May; 3. PMID: 38707479
Accumulating evidence suggests that infections may play a major role in Alzheimer's disease (AD), however, mechanism is unclear, as multiple pathways may be involved. One possibility is that infections could...