Konstantin E Orishchenko
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Explore the profile of Konstantin E Orishchenko including associated specialties, affiliations and a list of published articles.
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23
Citations
110
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Recent Articles
1.
Sergeeva S, Loshchenova P, Oshchepkov D, Orishchenko K
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39408734
Targeting DNA repair pathways is an important strategy in anticancer therapy. However, the unrevealed interactions between different DNA repair systems may interfere with the desired therapeutic effect. Among DNA repair...
2.
Posukh O, Maslova E, Danilchenko V, Zytsar M, Orishchenko K
Biomolecules
. 2023 Oct;
13(10).
PMID: 37892203
One of the most common forms of genetic deafness has been predominantly associated with pathogenic variants in the gene, encoding transmembrane protein connexin 26 (Cx26). The Cx26 molecule consists of...
3.
Danilchenko V, Zytsar M, Maslova E, Orishchenko K, Posukh O
Genes (Basel)
. 2023 Apr;
14(4).
PMID: 37107686
Pathogenic variants in the gene leading to nonsyndromic recessive deafness (DFNB4), or Pendred syndrome, are some of the most common causes of hearing loss worldwide. Earlier, we found a high...
4.
Karamysheva T, Gayner T, Elisaphenko E, Trifonov V, Zakirova E, Orishchenko K, et al.
Biomedicines
. 2022 Dec;
10(12).
PMID: 36552011
Detection and precise genomic mapping of balanced chromosomal abnormalities in patients with impaired fertility or a clinical phenotype represent a challenge for current cytogenomics owing to difficulties with precise breakpoint...
5.
Golubeva T, Cherenko V, Orishchenko K
Molecules
. 2021 Feb;
26(3).
PMID: 33572762
Selective regulation of gene expression by means of RNA interference has revolutionized molecular biology. This approach is not only used in fundamental studies on the roles of particular genes in...
6.
Zakirova E, Muzyka V, Mazunin I, Orishchenko K
Life (Basel)
. 2021 Jan;
11(2).
PMID: 33498399
The generally accepted theory of the genetic drift of mitochondrial alleles during mammalian ontogenesis is based on the presence of a selective bottleneck in the female germline. However, there is...
7.
Maslova E, Orishchenko K, Posukh O
Biomolecules
. 2021 Jan;
11(1).
PMID: 33466560
Mutations in the gene encoding transmembrane protein connexin 26 (Cx26) are the most common cause for hearing loss worldwide. Cx26 plays a crucial role in the ionic and metabolic homeostasis...
8.
Karamysheva T, Gayner T, Muzyka V, Orishchenko K, Rubtsov N
Genes (Basel)
. 2020 Dec;
11(12).
PMID: 33348590
For medical genetic counseling, estimating the chance of a child being born with chromosome abnormality is crucially important. Cytogenetic diagnostics of parents with a balanced karyotype are a special case....
9.
Menzorov A, Orishchenko K, Fishman V, Shevtsova A, Mungalov R, Pristyazhnyuk I, et al.
J Cell Biochem
. 2019 May;
120(10):17208-17218.
PMID: 31106442
Neuronal tracing is a modern technology that is based on the expression of fluorescent proteins under the control of cell type-specific promoters. However, random genomic integration of the reporter construct...
10.
Frolova T, Lipeeva A, Baev D, Baiborodin S, Orishchenko K, Kochetov A, et al.
Bioorg Chem
. 2018 Dec;
87:876-887.
PMID: 30538052
Fluorescent labeling is a widely-used approach in the study of intracellular processes. This method is becoming increasingly popular for studying small bioactive molecules of natural origin; it allows us to...