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Konstantin Dergilev

Explore the profile of Konstantin Dergilev including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Dergilev K, Gureenkov A, Parfyonova Y
Int J Mol Sci . 2024 Sep; 25(18). PMID: 39337582
The increasing burden of vascular dysfunction on healthcare systems worldwide results in higher morbidity and mortality rates across pathologies, including cardiovascular diseases. Vasculopathy is suggested to be caused by the...
2.
Zubkova E, Dergilev K, Beloglazova I, Kalinin A, Guseva A, Andreev A, et al.
Int J Mol Sci . 2023 Dec; 24(24). PMID: 38139105
Cardiosphere-derived cells (CDCs) are currently being evaluated in clinical trials as a potential therapeutic tool for regenerative medicine. The effectiveness of transplanted CDCs is largely attributed to their ability to...
3.
Dergilev K, Zubkova E, Guseva A, Tsokolaeva Z, Goltseva Y, Beloglazova I, et al.
Int J Mol Sci . 2023 Dec; 24(23). PMID: 38068898
Ischemic heart disease and its complications, such as myocardial infarction and heart failure, are the leading causes of death in modern society. The adult heart innately lacks the capacity to...
4.
Dergilev K, Tsokolaeva Z, Goltseva Y, Beloglazova I, Ratner E, Parfyonova Y
Int J Mol Sci . 2023 Nov; 24(21). PMID: 37958542
One of the largest challenges to the implementation of cardiac cell therapy is identifying selective reparative targets to enhance stem/progenitor cell therapeutic efficacy. In this work, we hypothesized that such...
5.
Beloglazova I, Zubkova E, Dergilev K, Goltseva Y, Parfyonova Y
Cells . 2022 Oct; 11(20). PMID: 36291145
A Matrigel-based tube formation assay is a simple and widely accepted 2D angiogenesis model in vitro. Extracellular matrix (EM) proteins and growth factors (GFs) from Matrigel exclusively trigger endothelial cell...
6.
Beloglazova I, Stepanova V, Zubkova E, Dergilev K, Koptelova N, Tyurin-Kuzmin P, et al.
Biochim Biophys Acta Mol Cell Res . 2021 Oct; 1869(1):119157. PMID: 34619163
Endothelial cells (ECs) degrade the extracellular matrix of vessel walls and contact surrounding cells to facilitate migration during angiogenesis, leading to formation of an EC-tubular network (ETN). Mesenchymal stromal cells...