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Kong Bung Choo

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Articles 21
Citations 314
Followers 0
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Recent Articles
1.
Huang C, Choo K
Gene . 2024 Dec; 940():149189. PMID: 39724991
Circular RNAs (circRNAs) are post-transcriptional regulators generated from backsplicing of pre-mRNAs of host genes. A major circRNA regulatory mechanism involves microRNA (miRNA) sequestering, relieving miRNA-blocked mRNAs for translation and functions....
2.
Rengganaten V, Huang C, Wang M, Chien Y, Tsai P, Lan Y, et al.
BMC Cancer . 2023 Nov; 23(1):1088. PMID: 37950151
Background: Cancer stem cells form a rare cell population in tumors that contributes to metastasis, recurrence and chemoresistance in cancer patients. Circular RNAs (circRNAs) are post-transcriptional regulators of gene expression...
3.
Huang C, Choo K
Int J Mol Sci . 2023 Mar; 24(5). PMID: 36901978
Adipogenesis is an indispensable cellular process that involves preadipocyte differentiation into mature adipocyte. Dysregulated adipogenesis contributes to obesity, diabetes, vascular conditions and cancer-associated cachexia. This review aims to elucidate the...
4.
Huang T, Chen C, Chen L, Lan Y, Huang T, Choo K, et al.
Front Pharmacol . 2022 Oct; 13:997100. PMID: 36267283
2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-Glucoside (THSG) is the main active ingredient extracted from Thunb. (PMT), which has been reported to possess extensive pharmacological properties. Nevertheless, the exact role of THSG in pulmonary fibrosis has...
5.
Huang C, Choo K, Chen C
Poult Sci . 2022 Jun; 101(8):101950. PMID: 35689996
Meat quality and nutritional value hinge on many factors, including fat content in the adipose tissue. In the adipogenesis process, stem cells are first committed to become preadipocytes, followed by...
6.
Cheng H, Huang C, Tsai M, Ong H, Cheong S, Choo K, et al.
Int J Med Sci . 2021 Mar; 18(8):1798-1809. PMID: 33746597
Cell migration and invasion are modulated by epithelial-to-mesenchymal transition (EMT) and the reverse MET process. Despite the detection of microRNA-362 (miR-362, both the miR-362-5p and -3p species) in cancers, none...
7.
Rengganaten V, Huang C, Tsai P, Wang M, Yang Y, Lan Y, et al.
Int J Mol Sci . 2020 Oct; 21(21). PMID: 33114016
Spheroidal cancer cell cultures have been used to enrich cancer stem cells (CSC), which are thought to contribute to important clinical features of tumors. This study aimed to map the...
8.
Tai L, Huang C, Choo K, Cheong S, Kamarul T
Int J Med Sci . 2020 Mar; 17(4):457-470. PMID: 32174776
Oxidative stress has been linked to senescence and tumorigenesis via modulation of the cell cycle. Using a hydrogen peroxide (HO)-induced oxidative stress-induced premature senescence (OSIPS) model previously reported by our...
9.
Hiew M, Cheng H, Huang C, Chong K, Cheong S, Choo K, et al.
J Biomed Sci . 2018 Jul; 25(1):57. PMID: 30025541
Background: Induced pluripotency in cancer cells by ectopic expression of pluripotency-regulating factors may be used for disease modeling of cancers. MicroRNAs (miRNAs) are negative regulators of gene expression that play...
10.
Nguyen P, Choo K, Huang C, Sugii S, Cheong S, Kamarul T
Stem Cell Res Ther . 2017 Oct; 8(1):214. PMID: 28962647
Background: Introduction of the transcription factors Oct4, Sox2, Klf4, and c-Myc (OSKM) is able to 'reprogram' somatic cells to become induced pluripotent stem cells (iPSCs). Several microRNAs (miRNAs) are known...