Kok Lung Chan
Overview
Explore the profile of Kok Lung Chan including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
6
Citations
1159
Followers
0
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Recent Articles
1.
Ying S, Minocherhomji S, Chan K, Palmai-Pallag T, Chu W, Wass T, et al.
Nat Cell Biol
. 2013 Jul;
15(8):1001-7.
PMID: 23811685
Fragile sites are chromosomal loci with a propensity to form gaps or breaks during early mitosis, and their instability is implicated as being causative in certain neurological disorders and cancers....
2.
Chan K, Hickson I
Semin Cell Dev Biol
. 2011 Jul;
22(8):906-12.
PMID: 21782962
Recent data indicate an unexpected requirement for proteins that were hitherto considered to be dedicated to DNA repair to facilitate the faithful disjunction of sister chromatids in anaphase. These include...
3.
Lukas C, Savic V, Bekker-Jensen S, Doil C, Neumann B, Pedersen R, et al.
Nat Cell Biol
. 2011 Feb;
13(3):243-53.
PMID: 21317883
Completion of genome duplication is challenged by structural and topological barriers that impede progression of replication forks. Although this can seriously undermine genome integrity, the fate of DNA with unresolved...
4.
5.
Chan K, Palmai-Pallag T, Ying S, Hickson I
Nat Cell Biol
. 2009 May;
11(6):753-60.
PMID: 19465922
Several inherited syndromes in humans are associated with cancer predisposition. The gene products defective in two of these disorders, BLM (a helicase defective in Bloom's syndrome) and FANC A-N (defective...
6.
Wu L, Chan K, Ralf C, Bernstein D, Garcia P, Bohr V, et al.
EMBO J
. 2005 Jul;
24(14):2679-87.
PMID: 15990871
Bloom's syndrome is a hereditary cancer-predisposition disorder resulting from mutations in the BLM gene. In humans, BLM encodes one of five members of the RecQ helicase family. One function of...