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Koji Yasutomo

Explore the profile of Koji Yasutomo including associated specialties, affiliations and a list of published articles. Areas
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Articles 90
Citations 2300
Followers 0
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Recent Articles
1.
Fujioka K, Nagai T, Hattori T, Kagami S, Yasutomo K, Galjart N, et al.
Nephrology (Carlton) . 2024 Oct; 29(12):815-824. PMID: 39350520
Aim: Several studies have shown that the progression of proteinuria and renal tissue injury is associated with activation of the intrarenal renin-angiotensin system (RAS). CCCTC-binding factor (CTCF) is a DNA-binding...
2.
Miyamura S, Oe R, Nakahara T, Koresawa H, Okada S, Taue S, et al.
Sci Rep . 2023 Sep; 13(1):14541. PMID: 37752134
Rapid, sensitive detection of biomolecules is important for biosensing of infectious pathogens as well as biomarkers and pollutants. For example, biosensing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is...
3.
Jaroonwitchawan T, Arimochi H, Sasaki Y, Ishifune C, Kondo H, Otsuka K, et al.
Front Immunol . 2023 Feb; 14:1065790. PMID: 36776885
FXR is a key molecule that modulates anti-inflammatory activity in the intestinal-liver axis. Although FXR has pleiotropic functions including regulation of liver inflammation and activation of macrophages, it remains unclear...
4.
Suzuki Y, Miyazaki T, Muto H, Kubara K, Mukai Y, Watari R, et al.
Mol Ther Nucleic Acids . 2022 Oct; 30:226-240. PMID: 36187052
mRNA and lipid nanoparticles have emerged as powerful systems for the preparation of vaccines against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The emergence of novel variants or the necessity...
5.
Tsukumo S, Subramani P, Seija N, Tabata M, Maekawa Y, Mori Y, et al.
Sci Adv . 2022 Aug; 8(34):eabq0008. PMID: 36001653
Immunoglobulin class switch recombination (CSR) plays critical roles in controlling infections and inflammatory tissue injuries. Here, we show that , a candidate gene for both rheumatoid arthritis and type 1...
6.
Kondo H, Kageyama T, Tanaka S, Otsuka K, Tsukumo S, Mashimo Y, et al.
Front Immunol . 2022 May; 13:836923. PMID: 35572546
BNT162b2, a nucleoside-modified mRNA vaccine for SARS-CoV-2 spike glycoprotein (S), provides approximately 95% efficacy for preventing COVID-19. However, it remains unclear how effectively memory CD8+ T cells are generated and...
7.
Sasaki Y, Arimochi H, Otsuka K, Kondo H, Tsukumo S, Yasutomo K
JCI Insight . 2022 Apr; 7(7). PMID: 35393946
Immunoproteasomes regulate the degradation of ubiquitin-coupled proteins and generate peptides that are preferentially presented by MHC class I. Mutations in immunoproteasome subunits lead to immunoproteasome dysfunction, which causes proteasome-associated autoinflammatory...
8.
Yano T, Kajisa T, Ono M, Miyasaka Y, Hasegawa Y, Saito A, et al.
Sci Rep . 2022 Jan; 12(1):1060. PMID: 35058513
The COVID-19 pandemic has created urgent demand for rapid detection of the SARS-CoV-2 coronavirus. Herein, we report highly sensitive detection of SARS-CoV-2 nucleocapsid protein (N protein) using nanoparticle-enhanced surface plasmon...
9.
Minamikawa T, Koma T, Suzuki A, Mizuno T, Nagamatsu K, Arimochi H, et al.
Sci Rep . 2021 Aug; 11(1):16221. PMID: 34349167
No abstract available.
10.
Boonchan M, Arimochi H, Otsuka K, Kobayashi T, Uehara H, Jaroonwitchawan T, et al.
Cell Death Dis . 2021 Jun; 12(6):601. PMID: 34112763
The sensing of various extrinsic stimuli triggers the receptor-interacting protein kinase-3 (RIPK3)-mediated signaling pathway, which leads to mixed-lineage kinase-like (MLKL) phosphorylation followed by necroptosis. Although necroptosis is a form of...