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Koji Kasamatsu

Explore the profile of Koji Kasamatsu including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 196
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Recent Articles
1.
Kawajiri T, Kijima A, Iimuro A, Ohashi E, Yamakawa K, Agura K, et al.
ACS Cent Sci . 2023 May; 9(4):836-843. PMID: 37122445
We describe the development of the practical manufacturing of Ensitrelvir, which was discovered as a SARS-CoV-2 antiviral candidate. Scalable synthetic methods of indazole, 1,2,4-triazole and 1,3,5-triazinone structures were established, and...
2.
Unoh Y, Uehara S, Nakahara K, Nobori H, Yamatsu Y, Yamamoto S, et al.
J Med Chem . 2022 Mar; 65(9):6499-6512. PMID: 35352927
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in millions of deaths and threatens public health and safety. Despite the rapid...
3.
Kasamatsu K, Yoshimura T, Mandi A, Taniguchi T, Monde K, Furuta T, et al.
Org Lett . 2017 Jan; 19(2):352-355. PMID: 28045272
A method for asymmetric α-arylation of α-amino acid derivatives via memory of chirality has been developed. Addition of axially chiral enolates, generated from α-amino acid derivatives, to in situ generated...
4.
Tomohara K, Kasamatsu K, Yoshimura T, Furuta T, Kawabata T
Chem Pharm Bull (Tokyo) . 2016 May; 64(7):899-906. PMID: 27150792
Enantioselective intramolecular conjugate addition reactions of short-lived C-O axially chiral enolates have been developed. The reactions proceeded with inversion of the configuration and provided dihydrobenzofurans with contiguous tetra- and trisubstituted...