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Koichiro Kawaguchi

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Articles 77
Citations 536
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Recent Articles
1.
Vu Q, Baba K, Sasaki S, Kawaguchi K, Hirano H, Osada H, et al.
Eur J Pharmacol . 2024 Feb; 969:176458. PMID: 38395373
Alantolactone is a eudesmane-type sesquiterpene lactone that exerts various biological effects, including anti-inflammatory activity. In the present study, screening using the RIKEN Natural Products Depository chemical library identified alantolactone derivatives...
2.
Xu J, Hashino T, Tanaka R, Kawaguchi K, Yoshida H, Kataoka T
Sci Rep . 2023 Aug; 13(1):14041. PMID: 37640805
The BCL-2 family protein BCL-RAMBO, also known as BCL2-like 13, anchors at the outer mitochondrial membrane and regulates apoptosis, mitochondrial fragmentation, and mitophagy. However, the mechanisms underlying the proapoptotic role...
3.
Matsuki Y, Sugihara T, Kihara T, Kawakami T, Kitaura T, Takata T, et al.
Viruses . 2023 Jul; 15(7). PMID: 37515132
COVID-19 is primarily known for its respiratory tract involvement, often leading to severe pneumonia and exacerbation of underlying diseases. However, emerging evidence suggests that COVID-19 can result in multiorgan failure,...
4.
Kawaguchi K, Ohashi T, Kobayashi N, Kanemoto K, Nose M, Shinozaki R, et al.
Biochim Biophys Acta Mol Cell Biol Lipids . 2023 Jul; 1868(9):159362. PMID: 37414211
Fatty acid-binding proteins (FABPs) are intracellular lipid-binding proteins that play roles in fatty acid transport and the regulation of gene expression. Dysregulated FABP expression and/or activity have been associated with...
5.
Okuda C, Ueda Y, Muroi M, Sanada E, Osada H, Shiono Y, et al.
J Antibiot (Tokyo) . 2023 Mar; 76(6):324-334. PMID: 36997727
Allantopyrone A is an α-pyrone metabolite that was originally isolated from the endophytic fungus Allantophomopsis lycopodina KS-97. We previously demonstrated that allantopyrone A exhibits anti-cancer, anti-inflammatory, and neuroprotective activities. In...
6.
Yashima K, Onoyama T, Kurumi H, Takeda Y, Yoshida A, Kawaguchi K, et al.
J Gastroenterol . 2023 Mar; 58(5):514. PMID: 36884074
No abstract available.
7.
Kamitani Y, Kurumi H, Kanda T, Ikebuchi Y, Yoshida A, Kawaguchi K, et al.
Medicine (Baltimore) . 2023 Mar; 102(9):e33033. PMID: 36862904
Ulcerative colitis (UC) causes a reduction in goblet cells. However, there have been few reports on the relationship between endoscopic and pathological findings and mucus volume. In this study, we...
8.
Kawaguchi K, Yoshida A, Yuki T, Shibagaki K, Tanaka H, Fujishiro H, et al.
Medicine (Baltimore) . 2023 Jan; 101(49):e32281. PMID: 36626498
Gastroduodenal peptic ulcers are the main cause of nonvariceal upper gastrointestinal bleeding (UGIB). We believe that recent advances in endoscopic techniques and devices for diagnosing upper gastrointestinal tract tumors have...
9.
Kawaguchi K, Asai A, Mikawa R, Ogiso N, Sugimoto M
Exp Anim . 2022 Oct; 72(2):173-182. PMID: 36288956
Aging is an extremely complex biological process, and various models, from unicellular organisms to mammals, have been used in its research. The mouse is the most widely used model for...
10.
Yashima K, Onoyama T, Kurumi H, Takeda Y, Yoshida A, Kawaguchi K, et al.
J Gastroenterol . 2022 Oct; 58(1):1-13. PMID: 36287268
Screening endoscopy has advanced to facilitate improvements in the detection and prognosis of gastric cancer. However, most early gastric cancers (EGCs) have subtle morphological or color features that are difficult...