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Koichiro Kano

Explore the profile of Koichiro Kano including associated specialties, affiliations and a list of published articles. Areas
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Articles 49
Citations 946
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Recent Articles
1.
Endo N, Matsumoto T, Kazama T, Kano K, Shimizu M, Ryu K, et al.
Regen Ther . 2024 Jun; 26:50-59. PMID: 38859891
Introduction: Mature adipocyte-derived dedifferentiated fat cells (DFATs) represent a subtype of multipotent cells that exhibit comparable phenotypic and functional characteristics to adipose-derived stem cells (ASCs). In this study, we assessed...
2.
Sawada H, Kazama T, Nagaoka Y, Arai Y, Kano K, Uei H, et al.
J Orthop Surg Res . 2023 Mar; 18(1):191. PMID: 36906634
Background: Mesenchymal stem cells (MSCs) are known to have different differentiation potential depending on the tissue of origin. Dedifferentiated fat cells (DFATs) are MSC-like multipotent cells that can be prepared...
3.
Utsunomiya K, Maruyama T, Shimizu S, Matsumoto T, Endo M, Kobayashi H, et al.
Stem Cell Res Ther . 2022 Jul; 13(1):319. PMID: 35842674
Introduction: The implantation of dedifferentiated fat (DFAT) cells has been shown to exert immunosuppressive effects. To develop DFAT cell therapy for antineutrophil cytoplasmic antibody (ANCA) glomerulonephritis, the effects of the...
4.
Uetaki M, Onishi N, Oki Y, Shimizu T, Sugihara E, Sampetrean O, et al.
Mol Biol Cell . 2022 Jun; 33(9):ar78. PMID: 35704469
Cellular differentiation is characterized by changes in cell morphology that are largely determined by actin dynamics. We previously showed that depolymerization of the actin cytoskeleton triggers the differentiation of preadipocytes...
5.
Akita D, Kazama T, Tsukimura N, Taniguchi Y, Takahashi R, Arai Y, et al.
Materials (Basel) . 2022 Feb; 15(4). PMID: 35207844
Adipose tissue is composed mostly of adipocytes that are in contact with capillaries. By using a ceiling culture method based on buoyancy, lipid-free fibroblast-like cells, also known as dedifferentiated fat...
6.
Murata Y, Obinata D, Matsumoto T, Ikado Y, Kano K, Fukuda N, et al.
Int Urol Nephrol . 2022 Feb; 54(4):789-797. PMID: 35175498
Purpose: Dedifferentiated fat (DFAT) cells are mature adipocyte-derived multipotent cells that can be applicable to cell-based therapy for stress urinary incontinence (SUI). This study developed a persistence SUI model that...
7.
Tanimoto K, Matsumoto T, Nagaoka Y, Kazama T, Yamamoto C, Kano K, et al.
Regen Ther . 2022 Jan; 19:35-46. PMID: 35059478
Introduction: Mature adipocyte-derived dedifferentiated fat cells (DFATs) are mesenchymal stem cell (MSC)-like cells with high proliferative ability and multilineage differentiation potential. In this study, we first examined whether DFATs can...
8.
Oki Y, Hagiwara R, Matsumaru T, Kano K
Genes Cells . 2021 Oct; 27(1):5-13. PMID: 34695306
Here, we established dedifferentiated fat (DFAT) cells from mature bovine adipocytes and then examined the effects of volatile fatty acids on the differentiation of these DFAT cells into adipocytes in...
9.
Hagiwara R, Oki Y, Matsumaru T, Ibayashi S, Kano K
Genes Cells . 2020 Oct; 25(12):811-824. PMID: 33064855
Mature adipocyte-derived dedifferentiated fat (DFAT) cells have been identified to possess similar multipotency to mesenchymal stem cells, but a method for converting DFAT cells into hepatocytes was previously unknown. Here,...
10.
Ishioka S, Hosokawa T, Ikeda T, Konuma N, Kaneda H, Ohashi K, et al.
Pediatr Surg Int . 2020 May; 36(7):799-807. PMID: 32448932
Purpose: Our previous studies demonstrated that mature adipocyte-derived dedifferentiated fat (DFAT) cells possess similar multipotency as mesenchymal stem cells. Here, we examined the immunoregulatory potential of DFAT cells in vitro...