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Koichi Takeuchi

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Articles 51
Citations 685
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Recent Articles
11.
Takeuchi K, Gertner M, Zhou J, Parada L, Bennett M, Zukin R
Proc Natl Acad Sci U S A . 2013 Mar; 110(12):4738-43. PMID: 23487788
The phosphoinositide signaling system is a crucial regulator of neural development, cell survival, and plasticity. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) negatively regulates phosphatidylinositol 3-kinase signaling and...
12.
Ishii-Nozawa R, Mita M, Shoji M, Takeuchi K
Biol Pharm Bull . 2012 Jul; 35(7):1091-5. PMID: 22791157
The Goto-Kakizaki (GK) rat is a non-obese and spontaneous model of mild Type 2 diabetes mellitus. In the present study, we compared the regulatory mechanisms of endogenous norepinephrine (NE) release...
13.
Udagawa T, Swanger S, Takeuchi K, Kim J, Nalavadi V, Shin J, et al.
Mol Cell . 2012 Jun; 47(2):253-66. PMID: 22727665
Translational control of mRNAs in dendrites is essential for certain forms of synaptic plasticity and learning and memory. CPEB is an RNA-binding protein that regulates local translation in dendrites. Here,...
14.
Takayasu Y, Takeuchi K, Kumari R, Bennett M, Zukin R, Francesconi A
Proc Natl Acad Sci U S A . 2010 Nov; 107(50):21778-83. PMID: 21098662
Group I metabotropic glutamate receptors (mGluR1/5) are important to synaptic circuitry formation during development and to forms of activity-dependent synaptic plasticity. Dysregulation of mGluR1/5 signaling is implicated in some disorders...
15.
Ishii-Nozawa R, Naito T, Mita M, Miyazaki K, Matsuda Y, Takeuchi K
Biol Pharm Bull . 2010 Jan; 33(1):150-2. PMID: 20045955
We examined the effects of chondroitinases on the release of dermatan sulfate (DS)-induced arginine amidase (AA) from rabbit ear artery. DS-induced AA release was significantly decreased by treatment with chondroitinase...
16.
Lau C, Takeuchi K, Rodenas-Ruano A, Takayasu Y, Murphy J, Bennett M, et al.
Biochem Soc Trans . 2009 Nov; 37(Pt 6):1369-74. PMID: 19909278
NMDARs (N-methyl-D-aspartate receptors) are critical for synaptic function throughout the CNS (central nervous system). NMDAR-mediated Ca(2+) influx is implicated in neuronal differentiation, neuronal migration, synaptogenesis, structural remodelling, long-lasting forms of...
17.
Kawarasaki T, Uchiyama K, Hirao A, Azuma S, Otake M, Shibata M, et al.
J Biomed Opt . 2009 Nov; 14(5):054017. PMID: 19895119
Animal imaging sources have become an indispensable material for biological sciences. Specifically, gene-encoded biological probes serve as stable and high-performance tools to visualize cellular fate in living animals. We use...
18.
Ito A, Ishii-Nozawa R, Ibuki C, Atarashi H, Kataoka H, Takeuchi K
Yakugaku Zasshi . 2009 Oct; 129(10):1239-47. PMID: 19797880
Epalrestat (Kinedak) is an aldose reductase inhibitor (ARI) for diabetic peripheral neuropathy. In 41 diabetics, we conducted a questionnaire survey to evaluate symptoms of peripheral neuropathy and select appropriate drug...
19.
Ishii-Nozawa R, Fujita K, Ise Y, Katayama S, Takeuchi K
Yakugaku Zasshi . 2009 Mar; 129(3):365-72. PMID: 19252395
When a fluticasone propionate (FP) diskhaler is used to administer inhaled corticosteroid, it has been reported that there is considerable drug residue remaining in the diskhaler after use. The internal...
20.
Kishi Y, Tanaka Y, Shibata H, Nakamura S, Takeuchi K, Masuda S, et al.
Cell Transplant . 2009 Jan; 17(9):1095-102. PMID: 19177845
Embryonic stem (ES) cells have the ability to generate teratomas when transplanted into immunodeficient mice, but conditions affecting the generation remain to be elucidated. Nonhuman primate cynomolgus ES cells were...