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Koichi Kubota

Explore the profile of Koichi Kubota including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 31
Followers 0
Related Specialties
Allergy & Immunology
Microbiology
Gastroenterology
Top 10 Co-Authors
Yuichi Kadoya
Yoshiko Inoue
Koya Obara
Atsushi Wake
Ming Zhao
Kazuma Yamaguchi
Michael Bouvet
Akira Tsuchiya
Kazuya Ishiwata
Akiko Masuda
Published In
Front Immunol
Microbiol Immunol
Cancer Genomics Proteomics
Hepatogastroenterology
Innate Immun
Affiliations
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Recent Articles
1.
Engineered Methioninase-expressing Tumor-targeting A1-R Inhibits Syngeneic-Cancer Mouse Models by Depleting Tumor Methionine
Kubota Y, Zhao M, Han Q, Aoki Y, Masaki N, Obara K, et al.
Cancer Genomics Proteomics . 2025 Feb; 22(2):247-257. PMID: 39993809
Background/aim: We previously developed A1-R, which selectively targets and kills tumors. In the present study, we established recombinant methioninase (rMETase)-producing A1-R (A1-R-rMETase), by transfer of the gene, to target methionine...
2.
Utility of liver stiffness measurement in the diagnosis of sinusoidal obstruction syndrome/veno-occlusive disease after hematopoietic stem cell transplantation
Inoue Y, Saitoh S, Denpo H, Yamaguchi K, Kubota K, Taya Y, et al.
J Med Ultrason (2001) . 2023 Dec; 51(2):311-321. PMID: 38112930
Purpose: We aimed to assess the role of liver stiffness measurement (LSM), evaluated using transient elastography (TE), for the diagnosis of sinusoidal obstruction syndrome (SOS)/veno-occlusive disease (VOD), a complication of...
3.
Phenotypic changes in growth-arrested T cell hybrids: a possible avenue to produce functional T cell hybridoma
Kubota K, Iwabuchi K
Front Immunol . 2014 Jun; 5:229. PMID: 24904579
No abstract available.
4.
IL-18 provided in dying bacterial-infected macrophages induces IFN-γ production in functional T-cell hybridoma B6HO3 through cell conjugates
Kubota K, Kadoya Y
Innate Immun . 2013 Jun; 20(2):133-44. PMID: 23723378
We have previously reported that the co-culture of functional T-cell hybridoma B6HO3 with dying J774 macrophage cells infected with Listeria monocytogenes (LM) results in the production of IFN-γ by B6HO3...
5.
Innate IFN-γ-producing cells in the spleen of mice early after Listeria monocytogenes infection: importance of microenvironment of the cells involved in the production of innate IFN-γ
Kubota K, Kadoya Y
Front Immunol . 2012 May; 2:26. PMID: 22566816
Production of innate interferon-γ (IFN-γ) is a crucial step in immunological defense against bacteria. However, there is little information regarding cellular mechanisms underlying IFN-γ production in vivo early after bacterial...
6.
A novel functional T cell hybridoma recognizes macrophage cell death induced by bacteria: a possible role for innate lymphocytes in bacterial infection
Kubota K
J Immunol . 2006 Jun; 176(12):7576-88. PMID: 16751404
We have established a novel TCRalphabeta (TCRVbeta6)(+)CD4(-)CD8(-) T cell hybridoma designated B6HO3. When the B6HO3 cells were cocultured with bacterial-infected J774 macrophage-like cells, IFN-gamma production by B6HO3 cells was triggered...
7.
Useful predictive factors of common bile duct stones prior to laparoscopic cholecystectomy for gallstones
Shiozawa S, Tsuchiya A, Kim D, Usui T, Masuda T, Kubota K, et al.
Hepatogastroenterology . 2005 Dec; 52(66):1662-5. PMID: 16334752
Background/aims: The aim of this study was to determine useful predictive factors of common bile duct stones (CBDs) as diagnosed by endoscopic retrograde cholangiopancreatography (ERCP) in patients who underwent laparoscopic...
8.
A structurally variant form of the 2B4 antigen is expressed on the cell surface of mouse mast cells
Kubota K
Microbiol Immunol . 2002 Oct; 46(8):589-92. PMID: 12363025
2B4 (CD244) is a 66-kDa CD2 family protein expressed on natural killer (NK) cells. Mouse NK cells express two isoforms of 2B4, termed 2B4L and 2B4S, whose molecular masses are...