Klaus Kunath
Overview
Explore the profile of Klaus Kunath including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
16
Citations
557
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Hugo M, Kunath K, Dressman J
Drug Dev Ind Pharm
. 2012 May;
39(2):402-12.
PMID: 22591213
Context: Along with other options, solid dispersions prepared by spray drying offer the possibility of formulating poorly soluble drugs in a rapidly dissolving format. As a wide range of potential...
2.
Vogt M, Vertzoni M, Kunath K, Reppas C, Dressman J
Eur J Pharm Biopharm
. 2007 Jul;
68(2):338-45.
PMID: 17646091
The oral bioavailability of EMD 57033, a calcium sensitizing agent with poor solubility, was compared in dogs using four solid dosage form formulation approaches: a physical blend of the drug...
3.
Vogt M, Kunath K, Dressman J
Eur J Pharm Biopharm
. 2007 Jun;
68(2):283-8.
PMID: 17574403
Several techniques were compared for improving the dissolution of fenofibrate, a poorly soluble drug. Particle size reduction was realized by jet milling (micronization; cogrinding with lactose, polyvinylpyrrolidone or sodium lauryl...
4.
Vogt M, Kunath K, Dressman J
Eur J Pharm Biopharm
. 2007 Jun;
68(2):330-7.
PMID: 17574401
The rate of the dissolution of four poorly soluble drugs (EMD 57033, albendazole, danazol and felodipine) was improved by cogrinding them with various excipients (lactose monohydrate, corn starch, polyvinylpyrrolidone, hydroxypropylmethyl...
5.
Merdan T, Kunath K, Petersen H, Bakowsky U, Voigt K, Kopecek J, et al.
Bioconjug Chem
. 2005 Jul;
16(4):785-92.
PMID: 16029019
The influence of PEGylation on polyplex stability from poly(ethylene imine), PEI, and plasmid DNA was investigated both in vitro and after intravenous administration in mice. Polyplexes were characterized with respect...
6.
Fischer D, Dautzenberg H, Kunath K, Kissel T
Int J Pharm
. 2004 Jul;
280(1-2):253-69.
PMID: 15265564
Poly(diallyldimethylammonium chlorides) (pDADMAC) of different molecular weights (5-244 kDa) and DADMAC/N-methyl-N-vinylacetamide (NMVA) copolymers (coDADMAC) with different composition (24-75 mol%) and therefore varying cationic charge densities were used to investigate the...
7.
Merdan T, Callahan J, Petersen H, Kunath K, Bakowsky U, Kopeckova P, et al.
Bioconjug Chem
. 2003 Sep;
14(5):989-96.
PMID: 13129403
Specific targeting of ovarian carcinoma cells using pegylated polyethylenimine (PEG-PEI) conjugated to the antigen binding fragment (Fab') of the OV-TL16 antibody, which is directed to the OA3 surface antigen, was...
8.
Kunath K, Merdan T, Hegener O, Haberlein H, Kissel T
J Gene Med
. 2003 Jun;
5(7):588-99.
PMID: 12825198
Background: Targeting to integrin receptor alpha(nu)beta(3) by RGD peptides seems to be a promising approach for gene delivery to proliferating endothelial cells of tumor metastases. PEGylation of cationic polymers offers...
9.
Kunath K, von Harpe A, Fischer D, Petersen H, Bickel U, Voigt K, et al.
J Control Release
. 2003 Apr;
89(1):113-25.
PMID: 12695067
Low-molecular-weight polyethylenimine (LMW-PEI) was synthesized by the acid-catalyzed, ring-opening polymerization of aziridine and compared with commercially available high-molecular-weight PEI (HMW-PEI) of 25 kDa. Molecular weights were determined by size-exclusion chromatography...
10.
Kunath K, von Harpe A, Fischer D, Kissel T
J Control Release
. 2003 Feb;
88(1):159-72.
PMID: 12586513
Complexes of galactosylated polyethylenimines (gal-PEI) with DNA have been proposed for gene delivery to hepatocytes. We synthesized gal-PEI with a broad range of degrees of substitution (DS) ranging from 3.5...