Klaske van Heusden
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Explore the profile of Klaske van Heusden including associated specialties, affiliations and a list of published articles.
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13
Citations
80
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Recent Articles
1.
Hosseinirad S, van Heusden K, Dumont G
J Clin Monit Comput
. 2023 Nov;
38(2):505-518.
PMID: 37934309
Inter-individual variability in Pharmacokinetic (PK) and Pharmacodynamic (PD) models significantly affects the accuracy of Target Controlled Infusion and closed-loop control of anesthesia. We hypothesize that the novel Eleveld PK model...
2.
van Heusden K, Stewart G, Otto S, Dumont G
PLOS Glob Public Health
. 2023 Mar;
3(2):e0000955.
PMID: 36962799
The COVID-19 pandemic has had an enormous toll on human health and well-being and led to major social and economic disruptions. Public health interventions in response to burgeoning case numbers...
3.
Napoleone G, van Heusden K, Cooke E, West N, Gorges M, Dumont G, et al.
Anesth Analg
. 2021 Feb;
133(5):1215-1224.
PMID: 33560659
Background: Closed-loop control of propofol-remifentanil anesthesia using the processed electroencephalography depth-of-hypnosis index provided by the NeuroSENSE monitor (WAVCNS) has been previously described. The purpose of this placebo-controlled study was to...
4.
Gonzalez-Cava J, Bagge Carlson F, Troeng O, Cervin A, van Heusden K, Dumont G, et al.
Comput Methods Programs Biomed
. 2020 Oct;
198:105783.
PMID: 33049452
Background And Objective: New proposals to improve the regulation of hypnosis in anaesthesia based on the development of advanced control structures emerge continuously. However, a fair study to analyse the...
5.
Wahlquist Y, van Heusden K, Dumont G, Soltesz K
Annu Int Conf IEEE Eng Med Biol Soc
. 2020 Oct;
2020:361-364.
PMID: 33018003
Closed-loop controlled drug dosing has the potential of revolutionizing clinical anesthesia. However, inter-patient variability in drug sensitivity poses a central challenge to the synthesis of safe controllers. Identifying a full...
6.
van Heusden K, Cooke E, Brodie S, West N, Gorges M, Dumont G, et al.
J Clin Monit Comput
. 2020 Apr;
35(3):557-567.
PMID: 32307624
Dose-dependent effects of ketamine on processed electroencephalographic depth-of-hypnosis indices have been reported. Limited data are available for the NeuroSENSE WAV index. Our aim was to establish the feasibility of closed-loop...
7.
van Heusden K, Soltesz K, Cooke E, Brodie S, West N, Gorges M, et al.
IEEE Trans Biomed Eng
. 2019 Feb;
66(10):2918-2923.
PMID: 30763237
Objective: The goal of this paper was to optimize robust PID control for propofol anesthesia in children aged 5-10 years to improve performance, particularly to decrease the time of induction...
8.
West N, McBeth P, Brodie S, van Heusden K, Sunderland S, Dumont G, et al.
J Clin Monit Comput
. 2018 Feb;
32(6):1081-1091.
PMID: 29464512
Sedation in the intensive care unit (ICU) is challenging, as both over- and under-sedation are detrimental. Current methods of assessment, such as the Richmond Agitation Sedation Scale (RASS), are measured...
9.
West N, van Heusden K, Gorges M, Brodie S, Rollinson A, Petersen C, et al.
Anesth Analg
. 2017 Dec;
127(4):883-894.
PMID: 29210791
Background: Closed-loop control of anesthesia involves continual adjustment of drug infusion rates according to measured clinical effect. The NeuroSENSE monitor provides an electroencephalographic measure of depth of hypnosis (wavelet-based anesthetic...
10.
Yousefi M, van Heusden K, Dumont G, Ansermino J
Annu Int Conf IEEE Eng Med Biol Soc
. 2016 Jan;
2015:454-7.
PMID: 26736297
In safety-critical control systems, such as closed-loop control of anesthesia, it is of utmost importance to guarantee the ability of a control approach to maintain states of the systems within...