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Kiyohiro Hamatani

Explore the profile of Kiyohiro Hamatani including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 191
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Recent Articles
1.
Hamatani K, Eguchi H, Koyama K, Mukai M, Nakachi K, Kusunoki Y
Oncol Rep . 2014 Sep; 32(5):1809-14. PMID: 25175022
During analysis of RET/PTC rearrangements in papillary thyroid cancer (PTC) among atomic bomb survivors, a cDNA fragment of a novel type of RET rearrangement was identified in a PTC patient...
2.
Taga M, Eguchi H, Shinohara T, Takahashi K, Ito R, Yasui W, et al.
Int J Clin Exp Pathol . 2012 Dec; 6(1):76-9. PMID: 23236545
Archival tissue specimens are valuable resources of materials for molecular biological analyses in retrospective studies, especially for rare diseases or those associated with exposure to uncommon environmental events. Although successful...
3.
Hamatani K, Mukai M, Takahashi K, Hayashi Y, Nakachi K, Kusunoki Y
Thyroid . 2012 Oct; 22(11):1153-9. PMID: 23050789
Background: We previously noted that among atomic bomb survivors (ABS), the relative frequency of cases of adult papillary thyroid cancer (PTC) with chromosomal rearrangements (mainly RET/PTC) was significantly greater in...
4.
Hamatani K, Eguchi H, Mukai M, Koyama K, Taga M, Ito R, et al.
Thyroid . 2009 Sep; 20(1):43-9. PMID: 19785523
Background: Since many thyroid cancer tissue samples from atomic bomb (A-bomb) survivors have been preserved for several decades as unbuffered formalin-fixed, paraffin-embedded specimens, molecular oncological analysis of such archival specimens...
5.
Hamatani K, Eguchi H, Ito R, Mukai M, Takahashi K, Taga M, et al.
Cancer Res . 2008 Sep; 68(17):7176-82. PMID: 18757433
A major early event in papillary thyroid carcinogenesis is constitutive activation of the mitogen-activated protein kinase signaling pathway caused by alterations of a single gene, typically rearrangements of the RET...
6.
Nakachi K, Hayashi T, Hamatani K, Eguchi H, Kusunoki Y
Mutat Res . 2008 Apr; 659(1-2):109-17. PMID: 18406659
This article provides an overview of the on-going molecular epidemiology studies among atomic-bomb survivors conducted at the Radiation Effects Research Foundation in Japan. The focus is on: (a) inter-individual variations...
7.
Yano M, Hamatani K, Eguchi H, Hirai Y, MacPhee D, Sugino K, et al.
Eur J Cancer . 2007 Mar; 43(6):1092-100. PMID: 17350822
Association of gene alterations and prognosis has not fully been elucidated in hepatocellular carcinoma (HCC). To clarify the relationship between p53 and hMSH2 mutations and prognosis, we analysed these mutations...
8.
Takahashi K, Eguchi H, Arihiro K, Ito R, Koyama K, Soda M, et al.
Mol Carcinog . 2006 Dec; 46(3):242-8. PMID: 17186541
In papillary thyroid carcinogenesis, the constitutively activated mitogen-activated protein (MAP) kinase signaling pathway caused by a genetic alteration such as RET/PTC rearrangement or mutation of RAS and BRAF genes, is...
9.
Hamatani K, Eguchi H, Takahashi K, Koyama K, Mukai M, Ito R, et al.
J Histochem Cytochem . 2006 Mar; 54(7):773-80. PMID: 16517976
Recently, in addition to DNA, RNA extracted from archival tissue specimens has become an invaluable source of material for molecular biological analysis. Successful amplification with PCR/RT-PCR is problematic when using...