Kishore R Alugupalli
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Explore the profile of Kishore R Alugupalli including associated specialties, affiliations and a list of published articles.
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34
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724
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Recent Articles
1.
Alugupalli K
Immunohorizons
. 2024 Aug;
8(8):527-537.
PMID: 39093309
Many bacterial polysaccharide vaccines, including the typhoid Vi polysaccharide (ViPS) and tetravalent meningococcal polysaccharide conjugate (MCV4) vaccines, do not incorporate adjuvants and are not highly immunogenic, particularly in infants. I...
2.
Alugupalli K
Front Immunol
. 2024 May;
15:1383476.
PMID: 38799439
None of the typhoid Vi Polysaccharide (ViPS) subunit vaccines incorporate adjuvants, and the immunogenicity of ViPS vaccines (e.g. Typbar TCV and Typhim Vi) is in part due to associated TLR4...
3.
Alugupalli K
Immunohorizons
. 2024 Apr;
8(4):317-325.
PMID: 38625118
Activation of the adaptive immune system requires the engagement of costimulatory pathways in addition to B and T cell Ag receptor signaling, and adjuvants play a central role in this...
4.
Alugupalli K
Immunohorizons
. 2024 Jan;
8(1):29-34.
PMID: 38180344
Activation of B cells and T cells requires the engagement of costimulatory signaling pathways in addition to Ag receptor signaling for efficient immune responses. None of the typhoid Vi polysaccharide...
5.
Alugupalli K, Kothari S, Cravens M, Walker J, Dougharty D, Dickinson G, et al.
Sci Rep
. 2023 Jan;
13(1):393.
PMID: 36624251
Salmonella enterica serovar Typhi is the causative agent of typhoid fever restricted to humans and does not replicate in commonly used inbred mice. Genetic variation in humans is far greater...
6.
Alugupalli A, Cravens M, Walker J, Gulandijany D, Dickinson G, Debes G, et al.
Immunohorizons
. 2022 Dec;
6(12):807-816.
PMID: 36480484
Circulating IgM present in the body prior to any apparent Ag exposure is referred to as natural IgM. Natural IgM provides protective immunity against a variety of pathogens. Salmonella enterica...
7.
Cheng M, Xu J, Ding K, Zhang J, Lu W, Liu J, et al.
Proc Natl Acad Sci U S A
. 2022 Oct;
119(42):e2205460119.
PMID: 36215473
Relapsing fever due to is characterized by recurrent bacteremia episodes. However, infection of , if not treated early, can spread to various organs including the central nervous system (CNS). CNS...
8.
Cravens M, Alugupalli A, Sandilya V, McGeady S, Alugupalli K
J Infect Dis
. 2022 Aug;
226(10):1852-1856.
PMID: 35932228
In mice, pneumococcal polysaccharide (PPS) vaccines generate antigen-specific immunoglobulin M (IgM) and immunoglobulins G1, G2, and G3. Antibody and complement-dependent opsonophagocytosis correlates with the protection induced by PPS vaccines in...
9.
Dickinson G, Levenson E, Walker J, Kearney J, Alugupalli K
J Immunol
. 2018 Jul;
201(4):1229-1240.
PMID: 30006375
Polysaccharide vaccines such as the Vi polysaccharide (ViPS) of serovar Typhi induce efficient Ab responses in adults but not in young children. The reasons for this difference are not understood....
10.
Belde V, Cravens M, Gulandijany D, Walker J, Palomo-Caturla I, Alugupalli A, et al.
Infect Immun
. 2018 Jul;
86(9).
PMID: 29967094
B cell antigen receptor (BCR) diversity increases by several orders of magnitude due to the action of terminal deoxynucleotidyl transferase (TdT) during V(D)J recombination. Unlike adults, infants have limited BCR...