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Kim Olievier

Explore the profile of Kim Olievier including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 238
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Recent Articles
1.
Coulon S, Legry V, Heindryckx F, Van Steenkiste C, Casteleyn C, Olievier K, et al.
Hepatology . 2013 Jan; 57(5):1793-805. PMID: 23299577
Unlabelled: The pathophysiology of nonalcoholic steatohepatitis (NASH) should be approached as a multifactorial process. In several stages of NASH, a link between disease progression and hepatic microvasculature changes can be...
2.
Heindryckx F, Kuchnio A, Casteleyn C, Coulon S, Olievier K, Colle I, et al.
J Hepatol . 2012 Mar; 57(1):61-8. PMID: 22420978
Background & Aims: The two major primary liver cancers in adults are hepatocellular carcinoma and cholangiocarcinoma. These tumors rapidly outgrow their vascular supply and become hypoxic, resulting in the production...
3.
Devisscher L, Hindryckx P, Olievier K, Peeters H, De Vos M, Laukens D
Biochem Biophys Res Commun . 2011 Nov; 416(3-4):307-12. PMID: 22108053
A positive-feedback mechanism between hypoxia-inducible factor 1 alpha (HIF-1α) and metallothioneins (MTs) has been identified in different diseases. Both proteins have been independently proposed in the pathogenesis of inflammatory bowel...
4.
Bogaert S, De Vos M, Olievier K, Peeters H, Elewaut D, Lambrecht B, et al.
PLoS One . 2011 Oct; 6(10):e25589. PMID: 22028783
Background: Endoplasmic reticulum (ER) stress has been suggested to play a role in inflammatory bowel disease (IBD). The three branches (ATF6, IRE1 and PERK) of the unfolded protein response (UPR)...
5.
Van Steenkiste C, Ribera J, Geerts A, Pauta M, Tugues S, Casteleyn C, et al.
Hepatology . 2011 Apr; 53(5):1629-40. PMID: 21520176
Unlabelled: Placental growth factor (PlGF) is associated selectively with pathological angiogenesis, and PlGF blockade does not affect the healthy vasculature. Anti-PlGF is therefore currently being clinically evaluated for the treatment...
6.
Bogaert S, Laukens D, Peeters H, Melis L, Olievier K, Boon N, et al.
BMC Immunol . 2010 Dec; 11:61. PMID: 21144017
Background: Immunological and genetic findings implicate Th17 effector cytokines in the pathogenesis of inflammatory bowel disease (IBD). Expression of Th17 pathway-associated genes is mainly studied in colonic disease. The present...
7.
Vanheule E, Fan Y, Van Huysse J, Meester D, Olievier K, Praet M, et al.
Eur J Gastroenterol Hepatol . 2010 Nov; 23(1):66-75. PMID: 21088600
Background/aims: Placental growth factor (PlGF) is known for its role in pathological conditions to protect parenchymal cells of different organs from injury, whereas its presence in the liver and its...
8.
Hindryckx P, De Vos M, Jacques P, Ferdinande L, Peeters H, Olievier K, et al.
J Immunol . 2010 Oct; 185(10):6306-16. PMID: 20943999
Hydroxylase inhibitors stabilize hypoxia-inducible factor-1 (HIF-1), which has barrier-protective activity in the gut. Because the inflammatory cytokine TNF-α contributes to inflammatory bowel disease in part by compromising intestinal epithelial barrier...
9.
Van Steenkiste C, Geerts A, Vanheule E, Van Vlierberghe H, de Vos F, Olievier K, et al.
Gastroenterology . 2009 Sep; 137(6):2112-24.e1-6. PMID: 19751735
Background & Aims: Portal hypertension is responsible for the major complications associated with cirrhosis. Angiogenesis has been associated with the pathophysiology of portal hypertension. We investigated the role of placental...