Kim E Haworth
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Explore the profile of Kim E Haworth including associated specialties, affiliations and a list of published articles.
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19
Citations
379
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Recent Articles
1.
Dong X, Lu Z, Kang C, Li X, Haworth K, Ma X, et al.
Arterioscler Thromb Vasc Biol
. 2021 Jan;
41(3):1191-1204.
PMID: 33406853
Objective: Noncoding RNAs are emerging as important players in gene regulation and cardiovascular diseases. Their roles in the pathogenesis of atherosclerosis are not fully understood. The purpose of this study...
2.
Wu P, Farrell W, Haworth K, Emes R, Kitchen M, Glossop J, et al.
Epigenetics
. 2016 Mar;
13(2):122-128.
PMID: 27019060
Several recent reports have described associations between gestational diabetes (GDM) and changes to the epigenomic landscape where the DNA samples were derived from either cord or placental sources. We employed...
3.
Kitchen M, Bryan R, Haworth K, Emes R, Luscombe C, Gommersall L, et al.
PLoS One
. 2015 Sep;
10(9):e0137003.
PMID: 26332997
Introduction: Inappropriate DNA methylation is frequently associated with human tumour development, and in specific cases, is associated with clinical outcomes. Previous reports of DNA methylation in low/intermediate grade non-muscle invasive...
4.
Glossop J, Haworth K, Emes R, Nixon N, Packham J, Dawes P, et al.
Epigenomics
. 2015 Jun;
7(4):539-51.
PMID: 26111028
Aim: Alterations in DNA methylation contribute to the abnormal phenotype of fibroblast-like synoviocytes (FLS) from patients with rheumatoid arthritis (RA). We profiled genome-wide DNA methylation in these cells from synovial...
5.
Haworth K, Farrell W, Emes R, Ismail K, Carroll W, Hubball E, et al.
Epigenomics
. 2014 Nov;
6(5):477-91.
PMID: 25431941
Aims: This study examined links between DNA methylation and birth weight centile (BWC), and explored the impact of genetic variation. Materials & Methods: Using HumanMethylation450 arrays, we examined candidate gene-associated...
6.
Glossop J, Emes R, Nixon N, Haworth K, Packham J, Dawes P, et al.
Epigenetics
. 2014 Aug;
9(9):1228-37.
PMID: 25147922
Changes to the DNA methylome have been described in patients with rheumatoid arthritis (RA). In previous work, we reported genome-wide methylation differences in T-lymphocyte and B-lymphocyte populations from healthy individuals....
7.
Glossop J, Nixon N, Emes R, Haworth K, Packham J, Dawes P, et al.
Epigenetics
. 2013 Sep;
8(11):1188-97.
PMID: 24005183
Multiple reports now describe changes to the DNA methylome in rheumatoid arthritis and in many cases have analyzed methylation in mixed cell populations from whole blood. However, these approaches may...
8.
Haworth K, Farrell W, Emes R, Ismail K, Carroll W, Borthwick H, et al.
Epigenomics
. 2013 Feb;
5(1):37-49.
PMID: 23414319
Aim: Evidence suggests that folic acid intake affects birth weight and that these effects may be mediated via the fetal epigenome. Our previous array data indicate that methylation in human...
9.
Emes R, Clifford H, Haworth K, Farrell W, Fryer A, Carroll W, et al.
Epilepsia
. 2012 Sep;
54(1):e16-9.
PMID: 23016625
Antiepileptic drugs (AEDs) can lower maternal folate and increase maternal homocysteine levels, which are known to affect the methyl cycle and hence DNA methylation levels. The influence of in utero...
10.
Fryer A, Emes R, Ismail K, Haworth K, Mein C, Carroll W, et al.
Epigenetics
. 2010 Sep;
6(1):86-94.
PMID: 20864804
Supplementation with folic acid during pregnancy is known to reduce the risk of neural tube defects and low birth weight. It is thought that folate and other one-carbon intermediates might...