Kieron J Sweeney
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Explore the profile of Kieron J Sweeney including associated specialties, affiliations and a list of published articles.
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21
Citations
65
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Recent Articles
1.
Dwivedi A, Mahesh A, Sanfeliu A, Larkin J, Siwicki R, Sweeney K, et al.
JCI Insight
. 2024 Nov;
10(1.
PMID: 39541170
The availability and integration of electrophysiological and molecular data from the living brain is critical in understanding and diagnosing complex human disease. Intracranial stereo electroencephalography (SEEG) electrodes used for identifying...
2.
Hashimoto Y, Greene C, Hanley N, Hudson N, Henshall D, Sweeney K, et al.
Fluids Barriers CNS
. 2024 Jun;
21(1):52.
PMID: 38898501
Claudin-5 is one of the most essential tight junction proteins at the blood-brain barrier. A single nucleotide polymorphism rs10314 is located in the 3'-untranslated region of claudin-5 and has been...
3.
Jagust P, Powell A, Ola M, Watson L, de Pablos-Aragoneses A, Garcia-Gomez P, et al.
J Natl Cancer Inst
. 2024 Jun;
116(10):1632-1644.
PMID: 38852945
Background: Breast cancer brain metastasis is a rising occurrence, necessitating a better understanding of the mechanisms involved for effective management. Breast cancer brain metastases diverge notably from the primary tumor,...
4.
Carton R, Doyle M, Kearney H, Steward C, Lench N, Rogers A, et al.
Epilepsia
. 2024 Mar;
65(5):1451-1461.
PMID: 38491957
Objective: The contribution of somatic variants to epilepsy has recently been demonstrated, particularly in the etiology of malformations of cortical development. The aim of this study was to determine the...
5.
Connor K, Conroy E, White K, Shiels L, Keek S, Ibrahim A, et al.
Sci Rep
. 2024 Feb;
14(1):2720.
PMID: 38302657
Here, we establish a CT-radiomics based method for application in invasive, orthotopic rodent brain tumour models. Twenty four NOD/SCID mice were implanted with U87R-Luc2 GBM cells and longitudinally imaged via...
6.
Pena-Ceballos J, Moloney P, Valentin A, ODonnell C, Colleran N, Liggan B, et al.
Seizure
. 2023 Oct;
112:98-105.
PMID: 37778300
Objective: Refractory idiopathic generalised epilepsy (IGE; also known as genetic generalised epilepsy) is a clinical challenge due to limited available therapeutic options. While vagus nerve stimulation (VNS) is approved as...
7.
Biswas A, Salvucci M, Connor K, Dussmann H, Carberry S, Fichtner M, et al.
J Neurooncol
. 2023 May;
163(2):327-338.
PMID: 37237151
Background: Glioblastoma (GBM) is an aggressive brain cancer that typically results in death in the first 15 months after diagnosis. There have been limited advances in finding new treatments for...
8.
Erthal L, Shi Y, Sweeney K, Gobbo O, Ruiz-Hernandez E
Sci Rep
. 2023 Mar;
13(1):5094.
PMID: 36991081
Malignant gliomas are a type of primary brain tumour that originates in glial cells. Among them, glioblastoma multiforme (GBM) is the most common and the most aggressive brain tumour in...
9.
Netufo O, Connor K, Shiels L, Sweeney K, Wu D, OShea D, et al.
Pharmaceuticals (Basel)
. 2022 May;
15(5).
PMID: 35631376
Glioblastoma (GBM) is the most aggressive adult brain tumour with a dismal 2-year survival rate of 26-33%. Maximal safe resection plays a crucial role in improving patient progression-free survival (PFS)....
10.
Sweeney K, Amoo M, Kilbride R, Jallo G, Javadpour M
Br J Neurosurg
. 2021 Aug;
38(3):746-751.
PMID: 34397316
The surgical management of brainstem glioma is challenging and has significant morbidity. Advances in surgical armamentarium has presented the opportunity to tackle these lesions. We present the case of a...