Kiara F Bruggeman
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Explore the profile of Kiara F Bruggeman including associated specialties, affiliations and a list of published articles.
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10
Citations
202
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Recent Articles
1.
Eivazi Zadeh Z, Nour S, Kianersi S, Jonidi Shariatzadeh F, Williams R, Nisbet D, et al.
iScience
. 2024 Aug;
27(8):110307.
PMID: 39156636
Neural diseases are challenging to treat and are regarded as one of the major causes of disability and morbidity in the world. Stem cells can provide a solution, by offering...
2.
Osouli-Bostanabad K, Masalehdan T, Kapsa R, Quigley A, Lalatsa A, Bruggeman K, et al.
ACS Biomater Sci Eng
. 2022 Jun;
8(7):2764-2797.
PMID: 35696306
Three-dimensional (3D) printing and 3D bioprinting are promising technologies for a broad range of healthcare applications from frontier regenerative medicine and tissue engineering therapies to pharmaceutical advancements yet must overcome...
3.
Wang Y, Bruggeman K, Franks S, Gautam V, Hodgetts S, Harvey A, et al.
Adv Healthc Mater
. 2020 Nov;
10(1):e2001238.
PMID: 33191667
Gene delivery has been extensively investigated for introducing foreign genetic material into cells to promote expression of therapeutic proteins or to silence relevant genes. This approach can regulate genetic or...
4.
Cembran A, Bruggeman K, Williams R, Parish C, Nisbet D
iScience
. 2020 Jan;
23(1):100788.
PMID: 31954980
The brain is a complex 3-dimensional structure, the organization of which provides a local environment that directly influences the survival, proliferation, differentiation, migration, and plasticity of neurons. To probe the...
5.
Bruggeman K, Williams R, Nisbet D
Adv Healthc Mater
. 2017 Dec;
7(1).
PMID: 29193871
Tissue engineering scaffolds are designed to mimic physical, chemical, and biological features of the extracellular matrix, thereby providing a constant support that is crucial to improved regenerative medicine outcomes. Beyond...
6.
Bruggeman K, Wang Y, Maclean F, Parish C, Williams R, Nisbet D
Nanoscale
. 2017 Sep;
9(36):13661-13669.
PMID: 28876347
Tissue-specific self-assembling peptide (SAP) hydrogels designed based on biologically relevant peptide sequences have great potential in regenerative medicine. These materials spontaneously form 3D networks of physically assembled nanofibres utilising non-covalent...
7.
Somaa F, Wang T, Niclis J, Bruggeman K, Kauhausen J, Guo H, et al.
Cell Rep
. 2017 Aug;
20(8):1964-1977.
PMID: 28834757
Stem cell transplants offer significant hope for brain repair following ischemic damage. Pre-clinical work suggests that therapeutic mechanisms may be multi-faceted, incorporating bone-fide circuit reconstruction by transplanted neurons, but also...
8.
Bruggeman K, Rodriguez A, Parish C, Williams R, Nisbet D
Nanotechnology
. 2016 Aug;
27(38):385102.
PMID: 27517970
Protein growth factors have demonstrated great potential for tissue repair, but their inherent instability and large size prevents meaningful presentation to biologically protected nervous tissue. Here, we create a nanofibrous...
9.
Horgan C, Rodriguez A, Li R, Bruggeman K, Stupka N, Raynes J, et al.
Acta Biomater
. 2016 May;
38:11-22.
PMID: 27131571
Unlabelled: The nanofibrillar structures that underpin self-assembling peptide (SAP) hydrogels offer great potential for the development of finely tuned cellular microenvironments suitable for tissue engineering. However, biofunctionalisation without disruption of...
10.
Wang T, Bruggeman K, Kauhausen J, Rodriguez A, Nisbet D, Parish C
Biomaterials
. 2015 Oct;
74:89-98.
PMID: 26454047
With the brain's limited capacity for repair there is a need for new and innovative therapies to promote regeneration. Stem/progenitor cell transplantation has received increasing attention, and whilst clinical trials...