Kher Shing Tan
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Explore the profile of Kher Shing Tan including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
71
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Recent Articles
1.
Thung T, Hall A, Jati A, White M, Bamert R, Tan K, et al.
mBio
. 2024 Oct;
15(12):e0256424.
PMID: 39475328
Importance: Bacteriophages (phages) are viruses that prey on bacteria. This study sampled natural phage populations to test the hypothesis that untapped genetic variation within a population can be the basis...
2.
Germany E, Thewasano N, Imai K, Maruno Y, Bamert R, Stubenrauch C, et al.
Elife
. 2024 Jan;
12.
PMID: 38226797
Outer membrane proteins (OMPs) are essential components of the outer membrane of Gram-negative bacteria. In terms of protein targeting and assembly, the current dogma holds that a 'β-signal' imprinted in...
3.
Dunstan R, Bamert R, Tan K, Imbulgoda U, Barlow C, Taiaroa G, et al.
Cell Rep
. 2023 May;
42(6):112551.
PMID: 37224021
To kill bacteria, bacteriophages (phages) must first bind to a receptor, triggering the release of the phage DNA into the bacterial cell. Many bacteria secrete polysaccharides that had been thought...
4.
Sakaue H, Shiota T, Ishizaka N, Kawano S, Tamura Y, Tan K, et al.
Mol Cell
. 2019 Feb;
73(5):1044-1055.e8.
PMID: 30738703
Mitochondria import nearly all of their resident proteins from the cytosol, and the TOM complex functions as their entry gate. The TOM complex undergoes a dynamic conversion between the majority...
5.
Jiang J, Tong J, Tan K, Gabriel K
Int J Mol Sci
. 2012 Sep;
13(7):8038-8050.
PMID: 22942688
β-barrel proteins are the highly abundant in the outer membranes of Gram-negative bacteria and the mitochondria in eukaryotes. The assembly of β-barrels is mediated by two evolutionary conserved machineries; the...
6.
Gorman M, Uboldi A, Walsh P, Tan K, Hansen G, Huyton T, et al.
Protein Sci
. 2011 Apr;
20(6):1060-8.
PMID: 21465610
Infection by Leishmania and Trypanosoma causes severe disease and can be fatal. The reduced effectiveness of current treatments is largely due to drug resistance, hence the urgent need to develop...
7.
Wlaschin K, Nissom P, de Leon Gatti M, Ong P, Arleen S, Tan K, et al.
Biotechnol Bioeng
. 2005 Jul;
91(5):592-606.
PMID: 16003777
Chinese hamster ovary (CHO) cells are one of the most important cell lines in biological research, and are the most widely used host for industrial production of recombinant therapeutic proteins....