Kewa Gao
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Explore the profile of Kewa Gao including associated specialties, affiliations and a list of published articles.
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19
Citations
432
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Recent Articles
1.
Gao K, Han H, Cranick M, Zhao S, Xu S, Yin B, et al.
ACS Nano
. 2024 Oct;
18(44):30293-30306.
PMID: 39445691
In utero gene editing with mRNA-based therapeutics has the potential to revolutionize the treatment of neurodevelopmental disorders. However, a critical bottleneck in clinical application has been the lack of mRNA...
2.
Zhao S, Gao K, Han H, Stenzel M, Yin B, Song H, et al.
Nat Nanotechnol
. 2024 Aug;
19(11):1702-1711.
PMID: 39179796
Lipid nanoparticle (LNP)-mRNA complexes are transforming medicine. However, the medical applications of LNPs are limited by their low endosomal disruption rates, high toxicity and long tissue persistence times. LNPs that...
3.
Xie B, Fan M, Wang C, Zhang Y, Xu S, Mizenko R, et al.
bioRxiv
. 2024 Mar;
PMID: 38496556
Significance: Mechanisms underlying aging-associated cancer risk remain unelucidated. This work demonstrates that polyploid giant cells (PGCs) in bone marrow mesenchymal stromal cells (BMSCs) from healthy female bone marrow donors can...
4.
Song H, Gao K, Hao D, Li A, Liu R, Anggito B, et al.
Front Pharmacol
. 2023 Mar;
14:1125209.
PMID: 36937891
The lack of vascularization associated with deep burns delays the construction of wound beds, increases the risks of infection, and leads to the formation of hypertrophic scars or disfigurement. To...
5.
Gao K, Li J, Song H, Han H, Wang Y, Yin B, et al.
Bioact Mater
. 2023 Feb;
25:387-398.
PMID: 36844366
Nanoparticle-based drug delivery systems have the potential to revolutionize medicine, but their low vascular permeability and rapid clearance by phagocytic cells have limited their medical impact. Nanoparticles delivered at the...
6.
Li T, Conroy K, Kim A, Halmai J, Gao K, Moreno E, et al.
Stem Cells
. 2023 Jan;
41(4):341-353.
PMID: 36639926
Human induced pluripotent stem cells (hiPSCs) not only provide an abundant source of vascular cells for potential therapeutic applications in vascular disease but also constitute an excellent model for understanding...
7.
He S, Walimbe T, Chen H, Gao K, Kumar P, Wei Y, et al.
Bioact Mater
. 2021 Dec;
10:460-473.
PMID: 34901560
Diabetic ischemic wound treatment remains a critical clinical challenge. Neovascularization plays a significant role in wound healing during all stages of the tissue repair process. Strategies that enhance angiogenesis and...
8.
Cai Y, Gao K, Peng B, Xu Z, Peng J, Li J, et al.
Front Pharmacol
. 2021 Dec;
12:781033.
PMID: 34899346
Alantolactone (ALT) is a natural compound extracted from Chinese traditional medicine with therapeutic potential in the treatment of various diseases. Recently, and studies have indicated cytotoxic effects of ALT on...
9.
Significance of TEAD Family in Diagnosis, Prognosis and Immune Response for Ovarian Serous Carcinoma
Ren X, Wang X, Peng B, Liang Q, Cai Y, Gao K, et al.
Int J Gen Med
. 2021 Nov;
14:7133-7143.
PMID: 34737608
Purpose: To explore the molecular profiles of transcriptional enhanced associate domain () family in ovarian serous carcinoma (OSC). Methods: In this study, we use bioinformatics methods including GEPIA, GE-mini, Oncomine...
10.
Xu Z, Peng B, Liang Q, Chen X, Cai Y, Zeng S, et al.
Front Immunol
. 2021 Oct;
12:719175.
PMID: 34603293
Ferroptosis is an iron-dependent cell death process that plays important regulatory roles in the occurrence and development of cancers, including hepatocellular carcinoma (HCC). Moreover, the molecular events surrounding aberrantly expressed...