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Kevin T Gray

Explore the profile of Kevin T Gray including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 63
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Recent Articles
1.
Gray K, Stefen H, Ly T, Keller C, Colpan M, Wayman G, et al.
Front Mol Neurosci . 2018 Oct; 11:357. PMID: 30356860
There are many unanswered questions about the roles of the actin pointed end capping and actin nucleation by tropomodulins (Tmod) in regulating neural morphology. Previous studies indicate that Tmod1 and...
2.
Arslan B, Colpan M, Gray K, Abu-Lail N, Kostyukova A
Arch Biochem Biophys . 2017 Dec; 638:18-26. PMID: 29223925
Tropomodulin family of proteins includes several isoforms of tropomodulins (Tmod) and leiomodins (Lmod). These proteins can sequester actin monomers or nucleate actin polymerization. Although it is known that their actin-binding...
3.
Gray K, Kostyukova A, Fath T
Mol Cell Neurosci . 2017 Apr; 84:48-57. PMID: 28433463
Actin is a profoundly influential protein; it impacts, among other processes, membrane morphology, cellular motility, and vesicle transport. Actin can polymerize into long filaments that push on membranes and provide...
4.
Gray K, Suchowerska A, Bland T, Colpan M, Wayman G, Fath T, et al.
Cytoskeleton (Hoboken) . 2016 Apr; 73(6):316-28. PMID: 27126680
Tropomodulins (Tmods) cap F-actin pointed ends and have altered expression in the brain in neurological diseases. The function of Tmods in neurons has been poorly studied and their role in...
5.
Colpan M, Moroz N, Gray K, Cooper D, Diaz C, Kostyukova A
Arch Biochem Biophys . 2016 Apr; 600:23-32. PMID: 27091317
The formation and fine-tuning of cytoskeleton in cells are governed by proteins that influence actin filament dynamics. Tropomodulin (Tmod) regulates the length of actin filaments by capping the pointed ends...
6.
Guillaud L, Gray K, Moroz N, Pantazis C, Pate E, Kostyukova A
Biochemistry . 2014 Apr; 53(16):2689-700. PMID: 24746171
Actin dynamics is fundamental for neurite development; monomer depolymerization from pointed ends is rate-limiting in actin treadmilling. Tropomodulins (Tmod) make up a family of actin pointed end-capping proteins. Of the...