Kevin Schofield
Overview
Explore the profile of Kevin Schofield including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
154
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0
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Recent Articles
1.
Wilms G, Schofield K, Maddern S, Foley C, Shaw Y, Smith B, et al.
J Med Chem
. 2024 Sep;
67(19):17259-17289.
PMID: 39344427
Small-molecule-induced protein degradation has emerged as a promising pharmacological modality for inactivating disease-relevant protein kinases. DYRK1A and DYRK1B are closely related protein kinases that are involved in pathological processes such...
2.
Schofield K, Maddern S, Zhang Y, Mastin G, Knight R, Wang W, et al.
Beilstein J Org Chem
. 2024 Sep;
20:2270-2279.
PMID: 39286789
The utility of bio-isosteres is broad in drug discovery and methodology herein enables the preparation of deuterium-labeled products is the most fundamental of known bio-isosteric replacements. As such we report...
3.
Strine M, Cai W, Wei J, Alfajaro M, Filler R, Biering S, et al.
PLoS Biol
. 2023 Jun;
21(6):e3002097.
PMID: 37310920
Identifying host genes essential for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has the potential to reveal novel drug targets and further our understanding of Coronavirus Disease 2019 (COVID-19). We...
4.
Abi-Raad R, Prasad M, Zheng J, Hui P, Ustun B, Schofield K, et al.
Am J Clin Pathol
. 2021 Feb;
156(1):100-108.
PMID: 33527115
Objectives: We investigate the potential role of BRAF testing in guiding surgical intervention in papillary thyroid carcinoma (PTC). Methods: Thyroid fine-needle aspiration (FNA) cases with available BRAF result and follow-up...
5.
Schofield K, Foley C, Hulme C
Org Lett
. 2020 Dec;
23(1):107-112.
PMID: 33306404
A 5- trig oxidative radical cyclization of benzylamine-derived Ugi three-component reaction products rapidly affords imidazolidinones with three diversity elements. This adaptation of our previously described multicomponent reaction-oxidation methodology further showcases...
6.
Abi-Raad R, Prasad M, Baldassari R, Schofield K, Callender G, Chhieng D, et al.
Endocr Pathol
. 2018 Jun;
29(3):269-275.
PMID: 29949024
The Bethesda System for reporting thyroid cytopathology (BSRTC) predicts an incidence of malignancy of less than 5% in thyroid nodules with a benign diagnosis on fine-needle aspiration (FNA). However, recent...
7.
Levi A, Bernstein J, Hui P, Duch K, Schofield K, Chhieng D
Arch Pathol Lab Med
. 2016 Feb;
140(2):153-7.
PMID: 26910220
Context: All Food and Drug Administration-approved methods in the United States for human papillomavirus testing including the Hybrid Capture 2 human papillomavirus assay and the Roche cobas human papillomavirus test...
8.
Carr R, Ustun B, Chhieng D, Schofield K, Theoharis C, Hammers L, et al.
Endocr Pathol
. 2013 Apr;
24(2):62-8.
PMID: 23595630
Various ultrasonographic characteristics of thyroid nodules have been associated with a higher likelihood of malignancy, and certain clinical features may also increase the likelihood of malignancy in patients. This study...
9.
Levi A, Galullo P, Gordy K, Mikolaiski N, Schofield K, Elsheikh T, et al.
Am J Clin Pathol
. 2012 Nov;
138(6):811-5.
PMID: 23161714
Studies examining the effects of increased workload on the performance of individual cytotechnologists are limited. Using FocalPoint GS, the performance of 3 cytotechnologists was evaluated. The study consisted of 3...
10.
Levi A, Beckman D, Hui P, Schofield K, Harigopal M, Chhieng D
Am J Clin Pathol
. 2012 Aug;
138(2):236-40.
PMID: 22904135
This study compared the performance of Chlamydia trachomatis testing using 2 methods: the BD ProbeTec Chlamydia trachomatis Q(x) Amplified DNA Assay (CTQ) on the BD Viper System with XTR technology...