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Kevin Ritter

Explore the profile of Kevin Ritter including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 31
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Recent Articles
1.
Chatterjee S, Preval L, Sin Z, Tran N, Ritter K, Su X, et al.
bioRxiv . 2024 Sep; PMID: 39345537
HDACs (histone deacetylase) play a crucial role in regulating gene expression, and the inhibition of these enzymes is gaining attention as a promising therapeutic approach for cancer treatment. Despite their...
2.
Haas T, Mundinger S, Qiu D, Jork N, Ritter K, Durr-Mayer T, et al.
Angew Chem Weinheim Bergstr Ger . 2024 Mar; 134(5):e202112457. PMID: 38505299
Stable isotope labelling is state-of-the-art in quantitative mass spectrometry, yet often accessing the required standards is cumbersome and very expensive. Here, a unifying synthetic concept for O-labelled phosphates is presented,...
3.
Wohlwend D, Merono L, Bucka S, Ritter K, Jessen H, Friedrich T
Structure . 2024 Mar; 32(6):715-724.e3. PMID: 38503292
Energy-converting NADH:ubiquinone oxidoreductase, respiratory complex I, is a major enzyme of energy metabolism that couples NADH oxidation and ubiquinone reduction with proton translocation. The NADH oxidation site features different enzymatic...
4.
Eisenbeis V, Qiu D, Gorka O, Strotmann L, Liu G, Prucker I, et al.
Proc Natl Acad Sci U S A . 2023 Aug; 120(34):e2306868120. PMID: 37579180
Inositol pyrophosphates (PP-InsPs) are energetic signaling molecules with important functions in mammals. As their biosynthesis depends on ATP concentration, PP-InsPs are tightly connected to cellular energy homeostasis. Consequently, an increasing...
5.
Ritter K, Jork N, Unmussig A, Kohn M, Jessen H
Biomolecules . 2023 Jul; 13(7). PMID: 37509185
Inositol phosphates constitute a family of highly charged messenger molecules that play diverse roles in cellular processes. The various phosphorylation patterns they exhibit give rise to a vast array of...
6.
Strotmann L, Harter C, Gerasimova T, Ritter K, Jessen H, Wohlwend D, et al.
Sci Rep . 2023 May; 13(1):7652. PMID: 37169846
NADH:ubiquinone oxidoreductase, respiratory complex I, plays a major role in cellular energy metabolism by coupling electron transfer with proton translocation. Electron transfer is catalyzed by a flavin mononucleotide and a...
7.
Qiu D, Gu C, Liu G, Ritter K, Eisenbeis V, Bittner T, et al.
Chem Sci . 2023 Feb; 14(3):658-667. PMID: 36741535
Technical challenges have to date prevented a complete profiling of the levels of -inositol phosphates (InsPs) and pyrophosphates (PP-InsPs) in mammalian tissues. Here, we have deployed capillary electrophoresis mass spectrometry...
8.
Gaugler P, Schneider R, Liu G, Qiu D, Weber J, Schmid J, et al.
Biochemistry . 2022 May; 61(12):1213-1227. PMID: 35640071
Inositol pyrophosphates are signaling molecules containing at least one phosphoanhydride bond that regulate a wide range of cellular processes in eukaryotes. With a cyclic array of phosphate esters and diphosphate...
9.
Haas T, Mundinger S, Qiu D, Jork N, Ritter K, Durr-Mayer T, et al.
Angew Chem Int Ed Engl . 2021 Nov; 61(5):e202112457. PMID: 34734451
Stable isotope labelling is state-of-the-art in quantitative mass spectrometry, yet often accessing the required standards is cumbersome and very expensive. Here, a unifying synthetic concept for O-labelled phosphates is presented,...
10.
Vranas M, Wohlwend D, Qiu D, Gerhardt S, Trncik C, Pervaiz M, et al.
Angew Chem Int Ed Engl . 2021 Oct; 60(52):27277-27281. PMID: 34612584
NADH:ubiquinone oxidoreductase, respiratory complex I, plays a central role in cellular energy metabolism. As a major source of reactive oxygen species (ROS) it affects ageing and mitochondrial dysfunction. The novel...