Kevin O Lillehei
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Explore the profile of Kevin O Lillehei including associated specialties, affiliations and a list of published articles.
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80
Citations
1554
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Recent Articles
1.
Anuzis A, Lillehei K
J Neurol Surg B Skull Base
. 2025 Jan;
86(1):46-57.
PMID: 39881744
The first line treatment for prolactinomas is currently dopamine agonists (DAs). Medical management is prolonged, associated with side effects, financial, and psychological burdens. In dedicated centers, pituitary surgery is a...
2.
Nguyen K, Graner A, Fringuello A, Zizzo Z, Valenzuela L, Anyanwu K, et al.
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684443
Chordomas are rare, generally slow-growing spinal tumors that nonetheless exhibit progressive characteristics over time, leading to malignant phenotypes and high recurrence rates, despite maximal therapeutic interventions. The tumors are notoriously...
3.
Wang M, Graner A, Knowles B, McRae C, Fringuello A, Paucek P, et al.
Neurol Int
. 2024 Nov;
16(6):1355-1384.
PMID: 39585062
Glioblastomas (GBMs) are dreadful brain tumors with abysmal survival outcomes. GBM extracellular vesicles (EVs) dramatically affect normal brain cells (largely astrocytes) constituting the tumor microenvironment (TME). We asked if EVs...
4.
Kiseljak-Vassiliades K, Lipe K, Turin C, Fishbein L, Costello J, Kerr J, et al.
J Neuropathol Exp Neurol
. 2024 May;
83(7):586-595.
PMID: 38777808
Corticotroph adenomas/pituitary neuroendocrine tumors (PitNETs) are associated with significant morbidity and mortality. Predictors of tumor behavior have not shown high prognostic accuracy. For somatotroph adenomas/PitNETs, E-cadherin expression correlates strongly with...
5.
Wang M, Graner A, Knowles B, McRae C, Fringuello A, Paucek P, et al.
bioRxiv
. 2024 Apr;
PMID: 38645117
Glioblastomas (GBMs) are dreadful brain tumors with abysmal survival outcomes. GBM EVs dramatically affect normal brain cells (largely astrocytes) constituting the tumor microenvironment (TME). EVs from different patient-derived GBM spheroids...
6.
Chatain G, Chee K, Driscoll M, Kleinschmidt-DeMasters B, Lillehei K
J Neurol Surg Rep
. 2024 Jan;
85(1):e1-e10.
PMID: 38213880
Collision tumors involving the sella are rare. Intrasellar collision tumors are most commonly composed of a combination of pituitary adenomas and pituitary neuroendocrine tumors; however, collision tumors consisting of a...
7.
Tatman P, Wroblewski T, Fringuello A, Scherer S, Foreman W, Damek D, et al.
J Neurol Surg B Skull Base
. 2023 Sep;
84(5):452-462.
PMID: 37671294
Epigenetics may predict treatment sensitivity and clinical course for patients with meningiomas more accurately than histopathology. Nonetheless, targeting epigenetic mechanisms is understudied for pharmacotherapeutic development for these tumors. The bio-molecular...
8.
Zhou W, Lovasz D, Zizzo Z, He Q, Coughlan C, Kowalski R, et al.
Biomedicines
. 2022 Nov;
10(11).
PMID: 36359238
Glioblastoma (GBM) is the most aggressive and lethal form of brain tumor. Extracellular vesicles (EVs) released by tumor cells play a critical role in cellular communication in the tumor microenvironment...
9.
Belanger K, Ung T, Damek D, Lillehei K, Ormond D
BMC Cancer
. 2022 Apr;
22(1):367.
PMID: 35392834
Background: High-grade and recurrent meningiomas are often treatment resistant and pose a therapeutic challenge after surgical and radiation therapy (RT) failure. Temozolomide (TMZ) is a DNA alkylating agent that appears...
10.
Callen A, Timpone V, Schwertner A, Zander D, Grassia F, Lennarson P, et al.
AJR Am J Roentgenol
. 2022 Mar;
219(2):292-301.
PMID: 35261281
Spontaneous intracranial hypotension (SIH) is a disorder of CSF dynamics that causes a complex clinical syndrome and severe disability. SIH is challenging to diagnose because of the variability of its...