Kevin M Biglan
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Explore the profile of Kevin M Biglan including associated specialties, affiliations and a list of published articles.
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51
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1574
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Recent Articles
1.
McCarthy A, Svensson K, Shanks E, Brittain C, Eastwood B, Kielbasa W, et al.
J Pharmacol Exp Ther
. 2021 Dec;
380(3):143-152.
PMID: 34893551
Dopamine (DA) plays a key role in several central functions including cognition, motor activity, and wakefulness. Although efforts to develop dopamine receptor 1 (D1) agonists have been challenging, a positive...
2.
Wilbraham D, Biglan K, Svensson K, Tsai M, Pugh M, Ardayfio P, et al.
Clin Pharmacol Drug Dev
. 2021 Oct;
11(3):324-332.
PMID: 34664427
Mevidalen (LY3154207) is a positive allosteric modulator of the dopamine D1 receptor that enhances the affinity of dopamine for the D1 receptor. The safety, tolerability, motor effects, and pharmacokinetics of...
3.
Wilbraham D, Biglan K, Svensson K, Tsai M, Kielbasa W
Clin Pharmacol Drug Dev
. 2020 Oct;
10(4):393-403.
PMID: 33029934
Activation of the brain dopamine D1 receptor has attracted attention because of its promising role in neuropsychiatric diseases. Although efforts to develop D1 agonists have been challenging, a positive allosteric...
4.
Tarolli C, Zimmerman G, Goldenthal S, Feldman B, Berk S, Siddiqi B, et al.
Neurol Clin Pract
. 2020 Mar;
10(1):7-14.
PMID: 32190415
Background: Use of video research visits in neurologic conditions is rising, but their utility has not been assessed in atypical parkinsonian syndromes. We sought to evaluate the diagnostic concordance between...
5.
Adams J, Dinesh K, Xiong M, Tarolli C, Sharma S, Sheth N, et al.
Digit Biomark
. 2020 Feb;
1(1):52-63.
PMID: 32095745
Background: Clinician rating scales and patient-reported outcomes are the principal means of assessing motor symptoms in Parkinson disease and Huntington disease. However, these assessments are subjective and generally limited to...
6.
Elson M, Stevenson E, Feldman B, Lim J, Beck C, Beran D, et al.
Telemed J E Health
. 2018 Jan;
24(9):722-724.
PMID: 29297769
Introduction: The integration of remote specialists into local care teams has not been widely evaluated. Methods: Therefore, we surveyed clinicians whose patients with Parkinson's disease had participated in a national...
7.
McGarry A, Biglan K
Handb Clin Neurol
. 2017 Sep;
144:93-98.
PMID: 28947128
Huntington disease (HD) is an autosomal-dominant, progressive neurodegenerative condition characterized by multiple movement disorders, psychiatric disturbances, and cognitive decline. As an insidious, progressive disorder, clinical phenoconversion in HD can be...
8.
Korn R, Wagle Shukla A, Katz M, Keenan H, Goldenthal S, Auinger P, et al.
Neurol Clin Pract
. 2017 Aug;
7(4):283-295.
PMID: 28840919
Background: Previous small-scale studies have demonstrated the feasibility of providing remote specialty care via virtual visits. We assessed the feasibility and benefits of a one-time consultation between a remote Parkinson...
9.
Beck C, Beran D, Biglan K, Boyd C, Ray Dorsey E, Schmidt P, et al.
Neurology
. 2017 Aug;
89(11):1152-1161.
PMID: 28814455
Objective: To determine whether providing remote neurologic care into the homes of people with Parkinson disease (PD) is feasible, beneficial, and valuable. Methods: In a 1-year randomized controlled trial, we...
10.
Mammen J, Elson M, Java J, Beck C, Beran D, Biglan K, et al.
Telemed J E Health
. 2017 Aug;
24(4):255-267.
PMID: 28787250
Materials And Methods: Qualitative survey data were collected from patients and physicians during a 12-month randomized controlled trial of virtual house calls for Parkinson's disease. Data from 149 cases were...