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Kevin J Kunstman

Explore the profile of Kevin J Kunstman including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 1291
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Recent Articles
11.
Ancuta P, Kamat A, Kunstman K, Kim E, Autissier P, Wurcel A, et al.
PLoS One . 2008 Jun; 3(6):e2516. PMID: 18575590
Elevated plasma lipopolysaccharide (LPS), an indicator of microbial translocation from the gut, is a likely cause of systemic immune activation in chronic HIV infection. LPS induces monocyte activation and trafficking...
12.
Kim E, Stanton J, Vega R, Kunstman K, Mirkin C, Wolinsky S
Nucleic Acids Res . 2006 Apr; 34(7):e54. PMID: 16617142
Here we report a real-time PCR-based method for determining the surface coverage of dithiol-capped oligonucleotides bound onto gold nanoparticles alone and in tandem with antibody. The detection of gold nanoparticle-bound...
13.
Ancuta P, Kunstman K, Autissier P, Zaman T, Stone D, Wolinsky S, et al.
Virology . 2005 Nov; 344(2):267-76. PMID: 16305804
The CD16+ subset of monocytes is dramatically expanded in peripheral blood during progression to AIDS, but its contribution to HIV pathogenesis is unknown. Here, we demonstrate that CD16+ but not...
14.
Layden-Almer J, Kuiken C, Ribeiro R, Kunstman K, Perelson A, Layden T, et al.
J Infect Dis . 2005 Aug; 192(6):1078-87. PMID: 16107963
In hepatitis C virus (HCV) infection, race is a determinant of treatment response and interferon (IFN) effectiveness. Here, we investigated whether there were differences in the pretreatment viral strains between...
15.
Barouch D, Powers J, Truitt D, Kishko M, Arthur J, Peyerl F, et al.
Nat Immunol . 2005 Feb; 6(3):247-52. PMID: 15685174
Viral escape from cytotoxic T lymphocytes (CTLs) can undermine immune control of human immunodeficiency virus 1. It is therefore important to assess the stability of viral mutations in CTL epitopes...
16.
Wolinsky S, Veazey R, Kunstman K, Klasse P, Dufour J, Marozsan A, et al.
Virology . 2004 Sep; 328(1):19-29. PMID: 15380354
Human immunodeficiency virus type 1 (HIV-1) fusion with its target cells is initiated by sequential interactions between its envelope glycoprotein, CD4, and a co-receptor, usually CCR5 or CXCR4. Small molecules...
17.
Kuhmann S, Pugach P, Kunstman K, Taylor J, Stanfield R, Snyder A, et al.
J Virol . 2004 Mar; 78(6):2790-807. PMID: 14990699
We have described previously the generation of an escape variant of human immunodeficiency virus type 1 (HIV-1), under the selection pressure of AD101, a small molecule inhibitor that binds the...
18.
Vogel T, Reynolds M, Fuller D, Vielhuber K, Shipley T, Fuller J, et al.
J Virol . 2003 Dec; 77(24):13348-60. PMID: 14645590
Given the current difficulties generating vaccine-induced neutralizing antibodies to human immunodeficiency virus (HIV), the focus of the vaccine community has shifted toward creating cytotoxic-T-lymphocyte (CTL)-based vaccines. Recent reports of CTL-based...
19.
Peyerl F, Barouch D, Yeh W, Bazick H, Kunstman J, Kunstman K, et al.
J Virol . 2003 Nov; 77(23):12572-8. PMID: 14610180
Virus-specific cytotoxic T lymphocytes (CTL) exert intense selection pressure on replicating simian immunodeficiency virus (SIV) and human immunodeficiency virus type 1 (HIV-1) in infected individuals. The immunodominant Mamu-A(*)01-restricted Gag p11C,...
20.
Ohagen A, Devitt A, Kunstman K, Gorry P, Rose P, Korber B, et al.
J Virol . 2003 Oct; 77(22):12336-45. PMID: 14581570
The genetic evolution of human immunodeficiency virus type 1 (HIV-1) in the brain is distinct from that in lymphoid tissues, indicating tissue-specific compartmentalization of the virus. Few primary HIV-1 envelope...