Keun-A Chang
Overview
Explore the profile of Keun-A Chang including associated specialties, affiliations and a list of published articles.
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74
Citations
1398
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Recent Articles
11.
Kim Y, Kim J, Kang S, Chang K
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37629191
Alzheimer's disease (AD) is one representative dementia characterized by the accumulation of amyloid beta (Aβ) plaques and neurofibrillary tangles (NFTs) in the brain, resulting in cognitive decline and memory loss....
12.
Kim K, Shin K, Chang K
Cells
. 2023 May;
12(9).
PMID: 37174709
Blood biomarkers have been considered tools for the diagnosis, prognosis, and monitoring of Alzheimer's disease (AD). Although amyloid-β peptide (Aβ) and tau are primarily blood biomarkers, recent studies have identified...
13.
Ko G, Kim J, Jeon Y, Lee D, Baek H, Chang K
Antioxidants (Basel)
. 2023 Apr;
12(4).
PMID: 37107160
(SM) has been used in oriental medicine for its neuroprotective effects against cardiovascular diseases and ischemic stroke. In this study, we investigated the therapeutic mechanism underlying the effects of SM...
14.
Yoo C, Kim J, Baek H, Chang K, Choe B
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982146
This study aimed to investigate morphological and metabolic changes in the brains of 5xFAD mice. Structural magnetic resonance imaging (MRI) and H magnetic resonance spectroscopy (MRS) were obtained in 10-...
15.
Jeon Y, Park S, Chang K, Baek H
Metabolites
. 2022 Dec;
12(12).
PMID: 36557229
Magnetic resonance spectroscopy (MRS) is a noninvasive technique for measuring metabolite concentration. It can be used for preclinical small animal brain studies using rodents to provide information about neurodegenerative diseases...
16.
Kim J, Kang S, Chang K
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142509
Alzheimer's disease (AD) is a form of dementia associated with abnormal glucose metabolism resulting from amyloid-beta (Aβ) plaques and intracellular neurofibrillary tau protein tangles. In a previous study, we confirmed...
17.
Jung D, Son G, Kwon O, Chang K, Moon C
Pharmaceutics
. 2022 Jul;
14(8).
PMID: 35893788
The key to current Alzheimer's disease (AD) therapy is the early diagnosis for prompt intervention, since available treatments only slow the disease progression. Therefore, this lack of promising therapies has...
18.
Tag S, Kim B, Bae J, Chang K, Im H
Mol Brain
. 2022 Jun;
15(1):51.
PMID: 35676711
Alzheimer's disease is associated with various brain dysfunctions, including memory impairment, neuronal loss, astrocyte activation, amyloid-β plaques, and neurofibrillary tangles. Transgenic animal models of Alzheimer's disease have proven to be...
19.
Kang S, Kim J, Lee S, Okamura N, Chang K
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628296
Alzheimer's disease (AD) is characterized by the deposition of extracellular amyloid plaques and intracellular accumulation of neurofibrillary tangles (NFT). Amyloid beta (Aβ) and tau imaging are widely used for diagnosing...
20.
Vu Nu T, Tran N, Nam E, Nguyen T, Yoon W, Cho S, et al.
RSC Adv
. 2022 May;
8(14):7855-7862.
PMID: 35539129
We present the immunoassay of tau proteins (total tau and phosphorylated tau) in human sera using surface plasmon resonance (SPR) fiber sensors. This assay aimed at harvesting the advantages of...