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Ketankumar Patel

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Articles 12
Citations 78
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Recent Articles
1.
Liang X, Pacula-Miszewska A, Vartak R, Prajapati M, Zheng H, Zhao C, et al.
Curr Issues Mol Biol . 2024 Mar; 46(3):2480-2496. PMID: 38534773
In the present work, we evaluated the antifungal activities of two novel ebselen analogs, -allyl-benzisoselenazol-3(2H)-one (-allyl-bs) and -3-methylbutylbenzisoselenazol-3(2H)-one (-3mb-bs). Colorimetric and turbidity assays were performed to determine the minimum inhibitory...
2.
Liang X, Pacula-Miszewska A, Obieziurska-Fabisiak M, Vartak R, Mao G, Patel K, et al.
Molecules . 2023 Nov; 28(21). PMID: 37959796
In the present work, a series of -terpenyl organoselenium compounds (CHB1-6) were evaluated for antimycotic activity by determining the minimum inhibitory concentration (MIC) for each compound in fluconazole (FLU)-sensitive (S1)...
3.
Liang X, Menon S, Vartak R, Gaida R, Wojaczynska E, Patel K, et al.
Nanomedicine (Lond) . 2023 Sep; 18(18):1195-1206. PMID: 37724540
Vulvovaginal candidiasis is primarily caused by (). Here, a novel organoselenium compound (G20) was synthesized and evaluated for anti- activity. Growth-inhibition studies and medium acidification assays to assess the inhibition...
4.
Pandya A, Vora L, Umeyor C, Surve D, Patel A, Biswas S, et al.
Adv Drug Deliv Rev . 2023 Jul; 200:115003. PMID: 37422267
Polymeric in situ forming depots have emerged as highly promising drug delivery systems for long-acting applications. Their effectiveness is attributed to essential characteristics such as biocompatibility, biodegradability, and the ability...
5.
Dong X, Zhang M, Cai C, Teng Q, Wang J, Fu Y, et al.
Front Pharmacol . 2022 Mar; 13:843829. PMID: 35281897
The KRAS-G12C inhibitor ARS-1620, is a novel specific covalent inhibitor of KRAS-G12C, possessing a strong targeting inhibitory effect on KRAS-G12C mutant tumors. Overexpression of ATP-binding cassette super-family B member 1...
6.
Menon S, Vartak R, Patel K, Billack B
Nanomedicine . 2021 Jul; 37:102428. PMID: 34217850
Vulvovaginal candidiasis (VVC), caused by Candida albicans, is a common infection in women affecting their quality of life. Standard antifungal drugs (e.g., fluconazole, itraconazole) are typically fungistatic or rendered ineffective...
7.
Menon S, Liang X, Vartak R, Patel K, Di Stefano A, Cacciatore I, et al.
Pharmaceutics . 2021 May; 13(5). PMID: 33946740
Carvacrol (CAR), a phenolic monoterpenoid, has been extensively investigated for its antimicrobial and antifungal activity. As a result of its poor physicochemical properties, water soluble carvacrol prodrugs (WSCPs) with improved...
8.
Wu Z, Yang Y, Wang J, Zhou W, Chen J, Fu Y, et al.
Front Pharmacol . 2021 Feb; 11:615824. PMID: 33519482
The emergence of multidrug resistance (MDR) has been a major issue for effective cancer chemotherapy as well as targeted therapy. One prominent factor that causes MDR is the overexpression of...
9.
Patki M, Palekar S, Nukala P, Vartak R, Patel K
AAPS PharmSciTech . 2020 Nov; 22(1):9. PMID: 33241538
Death from an accidental or intentional overdose of sleeping tablets has increased exponentially in the USA. Furthermore, the simultaneous consumption of sleeping tablets with alcoholic beverages not only intensifies the...
10.
Wu Z, Peng Z, Yang Y, Wang J, Teng Q, Lei Z, et al.
Front Oncol . 2020 Jun; 10:674. PMID: 32477940
M3814, also known as nedisertib, is a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor under phase 2 clinical trials. ABCG2 is a member of the ATP-binding cassette (ABC) transporter...