Kent E Williams
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Explore the profile of Kent E Williams including associated specialties, affiliations and a list of published articles.
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54
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Recent Articles
1.
Williams K, Zou Y, Qiu B, Kono T, Guo C, Garcia D, et al.
Cells
. 2024 Jan;
13(1).
PMID: 38201293
High levels of alcohol intake alter brain gene expression and can produce long-lasting effects. FK506-binding protein 51 (FKBP51) encoded by is a physical and cellular stress response gene and has...
2.
Qiu B, Zhong Z, Dou L, Xu Y, Zou Y, Weldon K, et al.
Cell Biosci
. 2024 Jan;
14(1):1.
PMID: 38167156
Background And Aims: Previously, we found that FK506 binding protein 51 (Fkbp51) knockout (KO) mice resist high fat diet-induced fatty liver and alcohol-induced liver injury. The aim of this research...
3.
Liang T, Kota J, Williams K, Saxena R, Gawrieh S, Zhong X, et al.
Int J Mol Sci
. 2023 Oct;
24(19).
PMID: 37834011
MicroRNA-29a (miR-29a) is a well characterized fibro-inflammatory molecule and its aberrant expression is linked to a variety of pathological liver conditions. The long-term effects of a high-fat diet (HFD) in...
4.
Qiu B, Zhong Z, Righter S, Xu Y, Wang J, Deng R, et al.
Cell Mol Life Sci
. 2022 Mar;
79(3):175.
PMID: 35244772
FK506-binding protein 51 (encoded by Fkpb51, also known as Fkbp5) has been associated with stress-related mental illness. To investigate its function, we studied the morphological consequences of Fkbp51 deletion. Artificial...
5.
Spence J, Lai D, Reiter J, Cao S, Bell R, Williams K, et al.
Alcohol
. 2020 Aug;
89:103-112.
PMID: 32798691
Background: Paternal alcohol abuse is a well-recognized risk factor for the development of an alcohol use disorder (AUD). In addition to genetic and environmental risk factors, heritable epigenetic factors also...
6.
Qiu B, Xu Y, Wang J, Liu M, Dou L, Deng R, et al.
Neuroscience
. 2019 Jan;
402:23-36.
PMID: 30685540
FKBP5 (FKBP51) is a glucocorticoid receptor (GR) binding protein, which acts as a co-chaperone of heat shock protein 90 (HSP90) and negatively regulates GR. Its association with mental disorders has...
7.
Spence J, Reiter J, Qiu B, Gu H, Garcia D, Zhang L, et al.
Front Genet
. 2018 Dec;
9:513.
PMID: 30564267
Humans show sex differences related to alcohol use disorders (AUD). Animal model research has the potential to provide important insight into how sex differences affect alcohol consumption, particularly because female...
8.
Jakeman L, Williams K, Brautigam B
Neural Regen Res
. 2014 Jul;
9(4):377-384.
PMID: 24999352
Glial cells in the central nervous system (CNS) contribute to formation of the extracellular matrix, which provides adhesive sites, signaling molecules, and a diffusion barrier to enhance efficient neurotransmission and...
9.
Williams K, Fulford L, Albig A
Cancer Microenviron
. 2011 Apr;
4(1):115-26.
PMID: 21505566
Matrikines are important components of tumor microenvironments that integrate communication between extracellular matricies and membrane-bound receptors thereby regulating cellular behaviors. One such matrikine that is differentially expressed in cancer microenvironments...
10.
Williams K, Voigt J
Hum Factors
. 2004 Sep;
46(2):288-303.
PMID: 15359678
The research reported herein presents the results of an empirical evaluation that focused on the accuracy and reliability of cognitive models created using a computerized tool: the cognitive analysis tool...