Kensuke Egashira
Overview
Explore the profile of Kensuke Egashira including associated specialties, affiliations and a list of published articles.
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Articles
158
Citations
6210
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Recent Articles
1.
Ikeda G, Matoba T, Ishikita A, Nagaoka K, Nakano K, Koga J, et al.
J Am Heart Assoc
. 2021 May;
10(12):e019521.
PMID: 34056918
Background The opening of mitochondrial permeability transition pore and inflammation cooperatively progress myocardial ischemia-reperfusion (IR) injury, which hampers therapeutic effects of primary reperfusion therapy for acute myocardial infarction. We examined...
2.
Matsumoto T, Yoshino S, Furuyama T, Morisaki K, Nakano K, Koga J, et al.
J Atheroscler Thromb
. 2021 Apr;
29(5):731-746.
PMID: 33907060
Aim: To assess the results of a phase I/IIa open-label dose-escalation clinical trial of 5-day repeated intramuscular administration of pitavastatin-incorporated poly (lactic-co-glycolic acid) nanoparticles (NK-104-NP) in patients with chronic limb...
3.
Katsuki S, Koga J, Matoba T, Umezu R, Nakashiro S, Nakano K, et al.
J Atheroscler Thromb
. 2021 Jan;
29(1):111-125.
PMID: 33455994
Aim: Abdominal aortic aneurysm (AAA) is a lethal and multifactorial disease. To prevent a rupture and dissection of enlarged AAA, prophylactic surgery and stenting are currently available. There are, however,...
4.
Sasaki K, Nishina S, Yamauchi A, Fukuda K, Hara Y, Yamamura M, et al.
Cell Mol Gastroenterol Hepatol
. 2020 Nov;
11(3):739-762.
PMID: 33191170
Background & Aims: Immune checkpoint inhibitors have shed light on the importance of antitumor immunity as a therapeutic strategy for hepatocellular carcinoma (HCC). The altered glucose metabolism known as the...
5.
Okahara A, Koga J, Matoba T, Fujiwara M, Tokutome M, Ikeda G, et al.
Sci Rep
. 2020 Sep;
10(1):14435.
PMID: 32879367
Ischemia-reperfusion injury impairs the efficacy of reperfusion therapy after ischemic stroke. Cyclophilin D (CypD)-mediated openings of mitochondrial permeability transition pore (mPTP) and subsequent monocyte-mediated inflammation are considered as major mechanisms...
6.
Yamashita S, Masuda D, Akishita M, Arai H, Asada Y, Dobashi K, et al.
J Atheroscler Thromb
. 2020 Sep;
27(11):1246-1254.
PMID: 32863291
No abstract available.
7.
Umezu R, Koga J, Matoba T, Katsuki S, Wang L, Hasuzawa N, et al.
Arterioscler Thromb Vasc Biol
. 2020 Jun;
40(7):e214-e226.
PMID: 32493171
Objective: Mitochondria consistently change their morphology in a process regulated by proteins, including Drp1 (dynamin-related protein 1), a protein promoting mitochondrial fission. Drp1 is involved in the mechanisms underlying various...
8.
Matsumoto T, Yamashita S, Yoshino S, Kurose S, Morisaki K, Nakano K, et al.
Ann Vasc Dis
. 2020 Apr;
13(1):4-12.
PMID: 32273916
Two decades have passed since therapeutic angiogenesis was proposed to promote reparative collateral growth as an alternative therapy for ischemic diseases in patients for whom neither surgical revascularization nor endovascular...
9.
Fujiwara M, Matoba T, Koga J, Okahara A, Funamoto D, Nakano K, et al.
Cardiovasc Res
. 2019 Mar;
115(7):1244-1255.
PMID: 30851101
Aims: Myocardial ischaemia-reperfusion (IR) injury hampers the therapeutic effect of revascularization in patients with acute myocardial infarction (AMI). Innate immunity for damage-associated protein patterns promotes the process of IR injury;...
10.
Ichimura K, Matoba T, Koga J, Nakano K, Funamoto D, Tsutsui H, et al.
Int Heart J
. 2018 Oct;
59(6):1432-1444.
PMID: 30369578
Statins are known to improve pulmonary arterial hypertension (PAH) by their anti-inflammatory and anti-proliferative effects in animal models. However, recent clinical studies have reported that clinically approved statin doses failed...