Kenneth D Brown
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Explore the profile of Kenneth D Brown including associated specialties, affiliations and a list of published articles.
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3
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85
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Recent Articles
1.
Apicomplexan rhomboids have a potential role in microneme protein cleavage during host cell invasion
Dowse T, Pascall J, Brown K, Soldati D
Int J Parasitol
. 2005 May;
35(7):747-56.
PMID: 15913633
Apicomplexan parasites secrete transmembrane (TM) adhesive proteins as part of the process leading to host cell attachment and invasion. These microneme proteins are cleaved in their TM domains by an...
2.
Pascall J, Brown K
Biochem Biophys Res Commun
. 2004 Mar;
317(1):244-52.
PMID: 15047175
Rhomboid-1 is a serine protease that cleaves the membrane domain of the Drosophila EGF-family protein, Spitz, to release a soluble growth factor. Several vertebrate rhomboid-like proteins have been identified, although...
3.
Pascall J, Luck J, Brown K
Biochem J
. 2002 Apr;
363(Pt 2):347-52.
PMID: 11931664
We report here distinct interdependent functions for two proteins, Star and Rhomboid, that are key determinants of the epidermal-growth-factor (EGF)-receptor signalling pathway in Drosophila. When we expressed the Drosophila EGF-receptor...