Kenneth A Barbee
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Explore the profile of Kenneth A Barbee including associated specialties, affiliations and a list of published articles.
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30
Citations
478
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Recent Articles
1.
Bhattacharyya A, Barbee K
Cytoskeleton (Hoboken)
. 2024 May;
81(9-10):473-487.
PMID: 38775643
Nitric oxide (NO) production by endothelial nitric oxide synthase (eNOS) inhibits platelet and leukocyte adhesion while promoting vasorelaxation in smooth muscle cells. Dysfunctional regulation of eNOS is a hallmark of...
2.
Muzorewa T, Buerk D, Jaron D, Barbee K
Cell Signal
. 2021 Sep;
87:110125.
PMID: 34474112
Background: Protein Kinase C (PKC) is a promiscuous serine/threonine kinase regulating vasodilatory responses in vascular endothelial cells. Calcium-dependent PKCbeta (PKCβ) and calcium-independent PKCeta (PKCη) have both been implicated in the...
3.
Muzorewa T, Buerk D, Jaron D, Barbee K
Nitric Oxide
. 2021 Apr;
111-112:1-13.
PMID: 33813098
Endothelial dysfunction, characterised by impaired nitric oxide (NO) bioavailability, arises in response to a variety of cardiovascular risk factors and precedes atherosclerosis. NO is produced by tight regulation of endothelial...
4.
Barbee K, Parikh J, Liu Y, Buerk D, Jaron D
Cell Mol Bioeng
. 2018 Oct;
11(2):143-155.
PMID: 30288177
Introduction: Colocalization of endothelial nitric oxide synthase (eNOS) and capacitative Ca entry (CCE) channels in microdomains such as cavaeolae in endothelial cells (ECs) has been shown to significantly affect intracellular...
5.
Liu Y, Buerk D, Barbee K, Jaron D
Microcirculation
. 2018 Jun;
25(6):e12465.
PMID: 29885064
Objectives: The effect of NO on smooth muscle cell contractility is crucial in regulating vascular tone, blood flow, and O delivery. Quantitative predictions for interactions between the NO production rate...
6.
Buerk D, Liu Y, Zaccheo K, Barbee K, Jaron D
Front Physiol
. 2018 Jan;
8:1053.
PMID: 29321744
Nitric oxide (NO) generated from nitrite through nitrite reductase activity in red blood cells has been proposed to play a major role in hypoxic vasodilation. However, we have previously predicted...
7.
Liu Y, Buerk D, Barbee K, Jaron D
Microvasc Res
. 2017 Apr;
112:79-86.
PMID: 28363495
Interactions between cardiac myoglobin (Mb), nitrite, and nitric oxide (NO) are vital in regulating O storage, transport, and NO homeostasis. Production of NO through the reduction of endogenous myocardial nitrite...
8.
Andrews A, Muzorewa T, Zaccheo K, Buerk D, Jaron D, Barbee K
Cell Mol Bioeng
. 2017 Feb;
10(1):30-40.
PMID: 28138348
Endothelial dysfunction, characterized by decreased production or availability of nitric oxide (NO), is widely believed to be the hallmark of early-stage atherosclerosis. In addition, hypercholesterolemia is considered a major risk...
9.
Liu Y, Buerk D, Barbee K, Jaron D
Nitric Oxide
. 2016 Aug;
60:1-9.
PMID: 27565833
Nitrite infusion into the bloodstream has been shown to elicit vasodilation and protect against ischemia-reperfusion injury through nitric oxide (NO) release in hypoxic conditions. However, the mechanism by which nitrite-derived...
10.
Kirby P, Buerk D, Parikh J, Barbee K, Jaron D
Nitric Oxide
. 2015 Nov;
52:1-15.
PMID: 26529478
We developed a mass transport model for a parallel-plate flow chamber apparatus to predict the concentrations of nitric oxide (NO) and adenine nucleotides (ATP, ADP) produced by cultured endothelial cells...