Kenkyo Matsuura
Overview
Explore the profile of Kenkyo Matsuura including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
141
Followers
0
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Recent Articles
1.
Kozawa K, Sekai M, Ohba K, Ito S, Sako H, Maruyama T, et al.
Curr Biol
. 2021 Jun;
31(14):3086-3097.e7.
PMID: 34087104
At the early stage of cancer development, oncogenic mutations often cause multilayered epithelial structures. However, the underlying molecular mechanism still remains enigmatic. By performing a series of screenings targeting plasma...
2.
Ueda M, Matsuura K, Kawai H, Wakasugi M, Matsunaga T
Genes Cells
. 2019 Feb;
24(4):284-296.
PMID: 30762924
The multisubunit complex transcription factor IIH (TFIIH) has dual functions in transcriptional initiation and nucleotide excision repair (NER). TFIIH is comprised of two subcomplexes, the core subcomplex (seven subunits) including...
3.
Robeson A, Lindblom K, Wojton J, Kornbluth S, Matsuura K
EMBO J
. 2018 Jun;
37(14).
PMID: 29875129
Caspase-2 has been shown to initiate apoptotic cell death in response to specific intracellular stressors such as DNA damage. However, the molecular mechanisms immediately upstream of its activation are still...
4.
Inagaki F, Momose M, Maruyama N, Matsuura K, Matsunaga T, Mukai C
Org Biomol Chem
. 2018 May;
16(23):4320-4324.
PMID: 29808899
Concisely synthesized and functionalized dihydroasparagusic acid (DHAA) derivatives were used to show that the introduction of a hydrophobic functional group dramatically reduced air oxidation activity at the dithiol moieties and...
5.
Kurokawa M, Kim J, Geradts J, Matsuura K, Liu L, Ran X, et al.
Sci Signal
. 2013 May;
6(274):ra32.
PMID: 23652204
In the intrinsic pathway of apoptosis, cell-damaging signals promote the release of cytochrome c from mitochondria, triggering activation of the Apaf-1 and caspase-9 apoptosome. The ubiquitin E3 ligase MDM2 decreases...
6.
Rsk-mediated phosphorylation and 14-3-3ɛ binding of Apaf-1 suppresses cytochrome c-induced apoptosis
Kim J, Parrish A, Kurokawa M, Matsuura K, Freel C, Andersen J, et al.
EMBO J
. 2012 Jan;
31(5):1279-92.
PMID: 22246185
Many pro-apoptotic signals trigger mitochondrial cytochrome c release, leading to caspase activation and ultimate cellular breakdown. Cell survival pathways, including the mitogen-activated protein kinase (MAPK) cascade, promote cell viability by...
7.
Matsuura K, Wakasugi M, Yamashita K, Matsunaga T
J Biol Chem
. 2008 Jun;
283(37):25485-25491.
PMID: 18550533
The Chk1 kinase is highly conserved from yeast to humans and is well known to function in the cell cycle checkpoint induced by genotoxic or replication stress. The activation of...
8.
Wakasugi M, Matsuura K, Nagasawa A, Fu D, Shimizu H, Yamamoto K, et al.
Biochem Biophys Res Commun
. 2007 Nov;
364(4):771-7.
PMID: 17976535
DDB1 was originally identified as a heterodimeric complex with DDB2 and plays an accessory role in nucleotide excision repair. DDB1 also constitutes an E3 ubiquitin ligase complex together with Cul4A...