Ken-Ichi Isobe
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Explore the profile of Ken-Ichi Isobe including associated specialties, affiliations and a list of published articles.
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Articles
103
Citations
6673
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Recent Articles
1.
Nishio N, Isobe K
J Anim Physiol Anim Nutr (Berl)
. 2023 Jan;
107(4):1110-1124.
PMID: 36688451
Hen eggs (eggs) are a conventional food, known to contain the nutrients required for the growth of chicken embryos. These eggs are rich in important proteins and fats, with a...
2.
Isobe K
Nihon Rinsho
. 2018 Dec;
74(9):1497-1501.
PMID: 30557483
Age-related decline of immune system not only increases susceptibility of infection, but also delays of wound healing. Although the number of innate immune cells such as neutro- phils and macrophages...
3.
Oh-Hashi K, Sugiura N, Amaya F, Isobe K, Hirata Y
Mol Cell Biochem
. 2017 Aug;
440(1-2):65-75.
PMID: 28825160
Activating transcription factor 4 (ATF4), which is ubiquitously expressed, plays a crucial role in regulating various stress-responsive genes under pathophysiological conditions. Further, growth arrest and DNA damage-inducible gene 34 (GADD34),...
4.
Nishio N, Hasegawa T, Tatsuno I, Isaka M, Isobe K
Geriatr Gerontol Int
. 2017 Jun;
17(12):2593-2601.
PMID: 28635009
Aim: To analyze the impact of sex on GADD34 function, we studied the aging of female GADD34-deficient mice and compared them with male GADD34-deficient mice. Methods: We used GADD34-deficient mice...
5.
Isobe K, Nishio N, Hasegawa T
World J Biol Chem
. 2017 Jun;
8(2):129-137.
PMID: 28588756
The proportion of elderly people rises in the developed countries. The increased susceptibility of the elderly to infectious diseases is caused by immune dysfunction, especially T cell functional decline. Age-related...
6.
Du Q, Tsuboi N, Shi Y, Ito S, Sugiyama Y, Furuhashi K, et al.
Am J Pathol
. 2016 Nov;
186(12):3176-3188.
PMID: 27855848
Macrophages are multifunctional immune cells that may either drive or modulate disease pathogenesis, depending on the activated phenotype. In this study, we investigated the protective effects of CD206 M2 macrophages...
7.
Liu L, Ito S, Nishio N, Sun Y, Tanaka Y, Isobe K
Anticancer Res
. 2016 Sep;
36(9):4623-8.
PMID: 27630304
Background: Tumor hypoxia induces the expression of growth arrest and DNA damage-inducible protein (GADD34). However, the role of GADD34 in tumor growth remains unclear. Materials And Methods: Gadd34 expression was...
8.
Tanaka Y, Ito S, Isobe K
Sci Rep
. 2016 Apr;
6:23920.
PMID: 27050089
Inflammatory bowel disease confers an increased risk of developing colitis-associated colon cancer (CAC). During the active colitis or developing tumor stage, commensal bacteria show dynamic translocation. However, whether alteration of...
9.
Yoshimura Y, Sano K, Isobe K, Aoki K, Kito M, Kato H
Int J Surg Case Rep
. 2016 Mar;
21:111-4.
PMID: 26967903
Introduction: We describe an unusual case of a uniformly high-grade malignant solitary fibrous tumor (SFT) of the thigh with recurrence after wide resection in a 31-year-old man. Presentation Of Case:...
10.
Klionsky D, Abdelmohsen K, Abe A, Abedin M, Abeliovich H, Arozena A, et al.
Autophagy
. 2016 Jan;
12(1):1-222.
PMID: 26799652
No abstract available.