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Keith M McLean

Explore the profile of Keith M McLean including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 447
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Recent Articles
1.
Henderson T, Ladewig K, Haylock D, McLean K, OConnor A
J Mater Chem B . 2020 Apr; 1(21):2682-2695. PMID: 32260973
The use of hydrogels as support materials for the growth and proliferation of mammalian cells has been well documented as they closely mimic the gel-like properties - and in some...
2.
Li L, Lu C, Wang L, Chen M, White J, Hao X, et al.
ACS Appl Mater Interfaces . 2018 Apr; 10(16):13283-13292. PMID: 29620862
In this study, an injectable, photocurable gelatin system, consisting of acrylated gelatin and thiolated gelatin, with tunable mechanical, biodegradation, and biological properties was used as a potential cell-supportive scaffold for...
3.
Cao L, Yu Y, Wang J, Werkmeister J, McLean K, Liu C
Mater Sci Eng C Mater Biol Appl . 2017 Mar; 74:298-306. PMID: 28254298
The aim of this study was to develop a 2-N, 6-O-sulfated chitosan (26SCS) modified electrospun fibrous PCL scaffold for bone morphogenetic protein-2 (BMP-2) delivery to improve osteoinduction. The PCL scaffold...
4.
Henderson T, Ladewig K, Haylock D, McLean K, OConnor A
J Biomater Sci Polym Ed . 2015 Jul; 26(13):881-97. PMID: 26123677
A facile method for the synthesis of cell supportive, highly macro-porous hyaluronic acid (HA) hydrogels via cryogelation is presented. Unmodified HA was chemically cross-linked via EDC/NHS zero-length cross-linking at sub-zero...
5.
Vashi A, White J, McLean K, Neethling W, Rhodes D, Ramshaw J, et al.
J Biomed Mater Res A . 2014 Oct; 103(6):1999-2005. PMID: 25266083
The present study has evaluated a commercial pericardial material for its capacity to assist as a natural extracellular matrix (ECM) patch for the delivery and retention of mesenchymal stem cells...
6.
Hartnett T, Ladewig K, OConnor A, Hartley P, McLean K
J Phys Chem B . 2014 Jun; 118(26):7430-9. PMID: 24915497
The effective use of lyotropic liquid crystalline dispersions, such as cubosomes, as drug delivery vehicles requires that they have tailored physical characteristics that suit specific therapeutics and external conditions. Here,...
7.
Mai-Prochnow A, Murphy A, McLean K, Kong M, Ostrikov K
Int J Antimicrob Agents . 2014 Mar; 43(6):508-17. PMID: 24637224
Cold atmospheric pressure plasma (APP) is a recent, cutting-edge antimicrobial treatment. It has the potential to be used as an alternative to traditional treatments such as antibiotics and as a...
8.
Cao L, Werkmeister J, Wang J, Glattauer V, McLean K, Liu C
Biomaterials . 2014 Jan; 35(9):2730-42. PMID: 24438908
Although rhBMP-2 has excellent ability to accelerate the repair of normal bone defects, limitations of its application exist in the high cost and potential side effects. This study aimed to...
9.
Salwiczek M, Qu Y, Gardiner J, Strugnell R, Lithgow T, McLean K, et al.
Trends Biotechnol . 2013 Nov; 32(2):82-90. PMID: 24176168
In order to colonize abiotic surfaces, bacteria and fungi undergo a profound change in their biology to form biofilms: communities of microbes embedded into a matrix of secreted macromolecules. Despite...
10.
Shen H, Lake V, Le Brun A, James M, Duff A, Peng Y, et al.
Biomaterials . 2013 Aug; 34(33):8361-9. PMID: 23899446
In this work we have formulated Annexin V (ANX) decorated phosphatidylserine containing phytantriol (PSPhy) cubosomes to act as probes for the enhanced detection of apoptotic membranes in both model and...