Keith J Johnson
Overview
Explore the profile of Keith J Johnson including associated specialties, affiliations and a list of published articles.
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12
Citations
157
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Recent Articles
1.
Johnson K, Sanchez H, Schoenbrunner N
Clin Rheumatol
. 2019 Sep;
38(11):2967-2976.
PMID: 31520227
Current guidelines recommend treating rheumatoid arthritis (RA) patients to reach low disease activity or remission, however, most biologic-naive RA patients fail to reach treatment targets on their first biologic therapy....
2.
Letzkus M, Luesink E, Starck-Schwertz S, Bigaud M, Mirza F, Hartmann N, et al.
Clin Transl Med
. 2015 May;
3:36.
PMID: 25984272
Background: Clinically useful biomarkers for patient stratification and monitoring of disease progression and drug response are in big demand in drug development and for addressing potential safety concerns. Many diseases...
3.
Versmissen J, Oosterveer D, Yazdanpanah M, Dehghan A, Holm H, Erdman J, et al.
Eur J Hum Genet
. 2014 Jun;
23(3):381-7.
PMID: 24916650
Mutations in the low-density lipoprotein receptor (LDLR) gene cause familial hypercholesterolemia (FH), a disorder characterized by coronary heart disease (CHD) at young age. We aimed to apply an extreme sampling...
4.
May A, Hazelhurst S, Li Y, Norris S, Govind N, Tikly M, et al.
BMC Genomics
. 2013 Sep;
14:644.
PMID: 24059264
Background: Due to the unparalleled genetic diversity of its peoples, Africa is attracting growing research attention. Several African populations have been assessed in global initiatives such as the International HapMap...
5.
Staedtler F, Hartmann N, Letzkus M, Bongiovanni S, Scherer A, Marc P, et al.
Biomarkers
. 2013 Jul;
18(5):436-45.
PMID: 23829492
Context: Correct gender assignment in humans at the molecular level is crucial in many scientific disciplines and applied areas. Materials And Methods: Candidate gender markers were identified through supervised statistical...
6.
Boyer O, Woerner S, Yang F, Oakeley E, Linghu B, Gribouval O, et al.
J Am Soc Nephrol
. 2013 May;
24(8):1216-22.
PMID: 23687361
LMX1B encodes a homeodomain-containing transcription factor that is essential during development. Mutations in LMX1B cause nail-patella syndrome, characterized by dysplasia of the patellae, nails, and elbows and FSGS with specific...
7.
Pluess-Li Y, Bongiovanni S, Oakeley E, Johnson K, Staedtler F
Drug Discov Today
. 2012 Apr;
17(17-18):1015-22.
PMID: 22521661
External access to scientific technology plays an increasingly important part in pharmaceutical R&D. One advantage of accessing technology externally is the avoidance of costs associated with purchase and the reduced...
8.
Williams J, Andersson T, Andersson T, Blanchard R, Behm M, Cohen N, et al.
J Clin Pharmacol
. 2008 Jun;
48(7):849-89.
PMID: 18524998
Pharmacogenomic (PGx) research on the absorption, distribution, metabolism, and excretion (ADME) properties of drugs has begun to have impact for both drug development and utilization. To provide a cross-industry perspective...
9.
Karim S, Johnson K, Griffiths I, Vouyiouklis D
Genomics
. 2004 Jan;
83(2):225-30.
PMID: 14706451
Hindshaker (hsh), a spontaneous, autosomal recessive mouse mutation, displays a developmentally dependent tremor of the hindquarters due to hypomyelination in the CNS. This myelin deficit is followed by progressive, but...
10.
Pall G, Johnson K, Smith G
Physiol Genomics
. 2003 Feb;
13(2):139-46.
PMID: 12595579
Dysfunction of the gene encoding DMPK (myotonic dystrophy protein kinase) has been implicated in the human neuromuscular disease myotonic dystrophy (DM1). The cardiac features of the disease include progressive conduction...