Keith A Crutcher
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Explore the profile of Keith A Crutcher including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
277
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Recent Articles
1.
Pettigrew D, Singh N, Kirthivasan S, Crutcher K
Medicina (Kaunas)
. 2022 Apr;
58(4).
PMID: 35454380
Unlike peripheral nerves, axonal regeneration is limited following injury to the spinal cord. While there may be reduced regenerative potential of injured neurons, the central nervous system (CNS) white matter...
2.
Pettigrew D, Dobson C, Isaacson L, Leuthardt E, Lilley H, Suidan G, et al.
PLoS One
. 2019 Sep;
14(9):e0216263.
PMID: 31487284
Explants of embryonic chick sympathetic and sensory ganglia were found to exhibit asymmetric radial outgrowth of neurites under standard culture conditions with or without exogenous Nerve Growth Factor [NGF]. Opposing...
3.
Richeri A, Bianchimano P, Crutcher K, Brauer M
Cell Tissue Res
. 2010 Apr;
340(2):287-301.
PMID: 20387079
In order to evaluate the contribution of substrate-bound factors to the extent and patterning of the sympathetic innervation of rat uterus following estrogen treatment, superior cervical ganglion explants from neonatal...
4.
Zhou W, Xu D, Peng X, Zhang Q, Jia J, Crutcher K
J Neurotrauma
. 2008 Apr;
25(4):279-90.
PMID: 18373478
There is conflicting evidence regarding a possible association between the apolipoprotein E4 (APOE4) allele and the consequences of traumatic brain injury (TBI). Our aim was to carry out a meta-analysis...
5.
Shelton S, Pettigrew D, Hermann A, Zhou W, Sullivan P, Crutcher K, et al.
J Neurosci Methods
. 2008 Jan;
168(2):431-42.
PMID: 18164073
A refined battery of neurological tests, SNAP (Simple Neuroassessment of Asymmetric Impairment), was developed and validated to efficiently assess neurological deficits induced in a mouse model of traumatic brain injury....
6.
Crutcher K, Gendelman H, Kipnis J, Perez-Polo J, Perry V, Popovich P, et al.
J Neuroimmune Pharmacol
. 2007 Nov;
1(3):195-211.
PMID: 18040798
No abstract available.
7.
Pettigrew D, Li Y, Kuntz 4th C, Crutcher K
Exp Neurol
. 2006 Sep;
203(1):95-109.
PMID: 16989811
Axonal regeneration is normally limited after injuries to CNS white matter. Infusion of neurotrophins has been successful in promoting regenerative growth through injured white matter but this growth generally fails...
8.
Dhanoa N, Krol K, Jahed A, Crutcher K, Kawaja M
Exp Neurol
. 2006 Feb;
198(2):416-26.
PMID: 16488412
Under normal conditions, expression of the p75 neurotrophin receptor (p75NTR) by sympathetic neurons can increase the affinity of the signaling receptor, trkA, to target-derived nerve growth factor (NGF) at distal...
9.
Dobson C, Sales S, Hoggard P, Wozniak M, Crutcher K
J Infect Dis
. 2006 Jan;
193(3):442-50.
PMID: 16388493
Background: The APOE genotype has a uniquely strong influence on the outcome of viral infection. The mechanism is unknown, although one possibility is direct inhibition of viral entry into cells....
10.
Bierl M, Jones E, Crutcher K, Isaacson L
Neurosci Lett
. 2005 Apr;
380(1-2):133-7.
PMID: 15854765
The classic neurotrophin hypothesis is based on the idea that innervating neurons derive 'mature' neurotrophin provided by the target for their survival. Yet large precursor forms of the neurotrophin nerve...