Keith A Crandall
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Explore the profile of Keith A Crandall including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Bernot J, Owen C, Wolfe J, Meland K, Olesen J, Crandall K
Mol Biol Evol
. 2023 Aug;
40(8).
PMID: 37552897
The clade Pancrustacea, comprising crustaceans and hexapods, is the most diverse group of animals on earth, containing over 80% of animal species and half of animal biomass. It has been...
12.
Dawson T, Rentia U, Sanford J, Cruchaga C, Kauwe J, Crandall K
Front Aging Neurosci
. 2023 Jul;
15:1186470.
PMID: 37484691
Introduction: Human endogenous retroviruses (HERVs) are transcriptionally-active remnants of ancient retroviral infections that may play a role in Alzheimer's disease. Methods: We combined two, publicly available RNA-Seq datasets with a...
13.
Kanholm T, Rentia U, Hadley M, Karlow J, Cox O, Diab N, et al.
Cancer Res
. 2023 May;
83(15):2584-2599.
PMID: 37249603
Significance: Analysis of epigenetic and transcriptional changes in a transformation model reveals that transposable element expression and methylation are dysregulated during oncogenic transformation.
14.
Yaparla A, Stern D, Hossainey M, Crandall K, Grayfer L
Dev Comp Immunol
. 2023 May;
146:104701.
PMID: 37196852
Macrophage-lineage cells are indispensable to immunity and physiology of all vertebrates. Amongst these, amphibians represent a key stage in vertebrate evolution and are facing decimating population declines and extinctions, in...
15.
Sun X, Liu Z, Li Z, Zeng Z, Peng W, Zhu J, et al.
Sci Rep
. 2023 Mar;
13(1):5141.
PMID: 36991079
Regulation of intron retention (IR), a form of alternative splicing, is a newly recognized checkpoint in gene expression. Since there are numerous abnormalities in gene expression in the prototypic autoimmune...
16.
Shumyatsky G, Burrell A, Chaney H, Sami I, Koumbourlis A, Freishtat R, et al.
Front Med (Lausanne)
. 2023 Jan;
9:1082125.
PMID: 36698799
Introduction: Pulmonary exacerbations (PEx) in persons with cystic fibrosis (CF) are primarily related to acute or chronic inflammation associated with bacterial lung infections, which may be caused by several bacteria...
17.
Hahn A, Burrell A, Chaney H, Sami I, Koumbourlis A, Freishtat R, et al.
Sci Rep
. 2023 Jan;
13(1):1217.
PMID: 36681756
Persons with cystic fibrosis (PwCF) suffer from pulmonary exacerbations (PEx) related in part to lung infection. While higher microbial diversity is associated with higher lung function, the data on the...
18.
Kassaye S, Grossman Z, Vengurlekar P, Chai W, Wallace M, Rhee S, et al.
Viruses
. 2023 Jan;
15(1).
PMID: 36680108
Background: Molecular epidemiological approaches provide opportunities to characterize HIV transmission dynamics. We analyzed HIV sequences and virus load (VL) results obtained during routine clinical care, and individual’s zip-code location to...
19.
Bustamante J, Dawson T, Loeffler C, Marfori Z, Marchesi J, Mullish B, et al.
Nutrients
. 2022 Dec;
14(24).
PMID: 36558359
Fecal microbiota transplantation (FMT) is a promising therapeutic modality for the treatment and prevention of metabolic disease. We previously conducted a double-blind, randomized, placebo-controlled pilot trial of FMT in obese...
20.
Inam Z, Felton E, Burrell A, Chaney H, Sami I, Koumbourlis A, et al.
Open Forum Infect Dis
. 2022 Sep;
9(9):ofac466.
PMID: 36168550
Background: Cystic fibrosis (CF) is characterized by recurrent pulmonary exacerbations (PEx) and lung function decline. PEx are frequently treated with antibiotics. However, little is known about the effects of antibiotics...